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tumor suppressor gene

   Also found in: Medical, Acronyms, Encyclopedia, Wikipedia 0.01 sec.
tumor suppressor gene
A gene that suppresses cellular proliferation. When inherited in a mutated state in which it is no longer suppressive, it is associated with the development of various cancers, including most familial cancers.
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.tumor suppressor gene - a suppressor gene that blocks unscheduled cell division
suppresser gene, suppressor gene, suppresser, suppressor - a gene that suppresses the phenotypic expression of another gene (especially of a mutant gene)


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All of these new pathways are important candidates for novel tumor suppressor genes and could be involved in cancer progression.
9781604563269 Tumor suppressor genes in breast cancer.
Previous studies have shown that miR-21 interrnpts the activity of two tumor suppressor genes, PTEN (for phosphatase and tensin homolog) and TPM1 (tropomyosin 1).
 
 
 
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