References in periodicals archive ?
Daiichi Sankyo Company, Limited announced the first patient has been dosed in a phase 1 study assessing the safety and tolerability of DS-1062, an investigational TROP2-targeting antibody drug conjugate (ADC), in patients with unresectable advanced non-small cell lung cancer (NSCLC) who are refractory to or have relapsed following standard treatment or for whom no standard treatment is available.
M2 PHARMA-February 19, 2018-AstraZeneca wins US FDA approval for IMFINZI (durvalumab) for treating unresectable Stage III non-small cell lung cancer
M2 EQUITYBITES-February 19, 2018-AstraZeneca wins US FDA approval for IMFINZI (durvalumab) for treating unresectable Stage III non-small cell lung cancer
BeiGene announced that the first patient was dosed in a global Phase 3 clinical trial of tislelizumab, an investigational anti-PD-1 antibody, as a potential second-line treatment in patients with advanced unresectable or metastatic esophageal squamous cell carcinoma.
Background: Controversy exists over whether aggressive surgical resection of the primary tumor without metastasectomy first or chemotherapy first in stage IV colon cancer with unresectable synchronous liver-only-metastases (CLM) improves patients.
Pembrolizumab, the programmed-death receptor-l-blocking antibody, is now approved as a first-line treatment of unresectable or metastatic melanoma, based on the results of the KEYNOTE-006 study.
Two drugs that target mutations on the BRAF gene have been approved for treating metastatic or unresectable melanomas that express the mutations--along with a companion test to detect the mutations, the Food and Drug Administration announced.
1,2) Although numerous studies have evaluated the effects of chemoradiotherapy (CRT), including cost-effectiveness for locally advanced HNC, sometimes called unresectable but not defined, (3-7) few investigations have described the criteria of unresectability and outcomes of patients with stage IVB HNC (8-10) treated exclusively by CRT.
Cetuximab in combination with 5-fluorouracil, leucovorin and irinotecan as a neoadjuvant chemotherapy in patients with initially unresectable colorectal liver metastases
Merck KGaA, Darmstadt, Germany, has announced that the first patient has been enrolled in its global Phase III clinical study, START (Stimulating Targeted Antigenic Responses To NSCLC), assessing the efficacy and safety of Stimuvax (BLP25 liposome vaccine) as a potential treatment for patients with unresectable stage III non-small cell lung cancer (NSCLC).
Surgery is the primary treatment; chemotherapy is reserved for patients with unresectable disease and for those with positive tumor margins.
DENVER -- Laparoscopic radiofrequency ablation of hepatocellular carcinoma may enhance survival in patients with unresectable disease, Dr.