Changes to the DNA; determination of DNA adducts or DNA strand breakages, or measurement of unscheduled DNA synthesis
as a cellular response to DNA damage.
17-19 Areca nut extract also induces unscheduled DNA synthesis by cultured gingival keratinocytes.
Study of unscheduled DNA synthesis following exposure of human cells to arecoline and extracts of betel nut in vitro.
2002): DNA repair capacity, as measured by unscheduled DNA synthesis
following exposure to UV light, is reduced in lymphocytes from heroin addicts (Madden et al.
Spontaneous DNA synthesis (DS) and unscheduled DNA synthesis
(UDS) were assayed with a liquid scintillation counter (Beckman Coulter Inc.
Chromosome aberrations, Sister chromatid exchanges, unscheduled DNA synthesis
and morphological neoplastic transformation in Syrian hamster embryo cells.
Complying with FDA 21 CFR Part 11 final rule, for R&D and quality assurance testing, the system is suitable for colony counting and sizing, unscheduled DNA synthesis
, Ames testing Chemotaxiz, Elispot assay, MIC assays, and other life science applications.
Using Syrian hamster embryo (SHE) cells, phenol induced morphologic transformations, gene mutations at two loci (both ouabain-resistant and 6-thioguanine-resistant mutant frequencies were increased), chromosomal aberrations, sister chromatid exchanges, and unscheduled DNA synthesis