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Related to uricosuric: Uricosuric agents, probenecid, pegloticase


Promoting the excretion of uric acid in the urine.

[From uric + uric.]


(Biology) increasing or promoting the excretion of uric acid in urine
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Adj.1.uricosuric - acting to increase the excretion of uric acid in the urine
References in periodicals archive ?
The commonly used urate-lowering agents in clinical practice include two classes: urate production inhibitors and uricosuric agents.
In addition, hyperuricemia was also noted and controlled by uricosuric agents postoperatively.
Benzbromarone, an old uricosuric drug, inhibits human fatty acid binding protein 4 in vitro and lowers the blood glucose level in db/db mice.
in a study on Chinese diabetic patients found that hyperuricemia was significantly associated with abnormal albuminuria in patients without diuretics or use of uricosuric agents or alcohol.
Angiotensin receptor blockers have a mild uricosuric effect and may help with lowering uric acid levels.
Several options for lowering sUA are available, including xanthine oxidase inhibitors (allopurinol, febuxostat) that prevent the production of uric acid, uricosuric agents (probenecid), and one biologic agent (pegloticase) that enzymatically degrades uric acid to allantoin.
Members of the Food and Drug Administration's Arthritis Advisory Committee have voted in favor of recommending approval of the investigational uricosuric drug lesinurad at 200 mg daily for the proposed indication of treatment of hyperuricemia associated with gout in combination with a xanthine oxidase inhibitor, such as allopurinol or febuxostat.
Hence, for patients suffering from Gout or elderly drugs like Losartan potassium, captopril or Enalapril are preferred as they are effective in treating Hyperuricemia and gout complicated by hypertension because of their combined hypotensive and uricosuric effects.
Losartan is a weak uricosuric and can lower the serum urate level slightly, possibly making the addition of another hypouricemic agent unnecessary, while still controlling the blood pressure with a single pill," Dr.
Diuretic, antilithiasic, uricosuric and antiseptic properties are usually accredited to corn silk, style/stigma of maize (Zea mays L.
Treatment options may include uricosuric agents that enhance uric acid excretion, xanthine oxidase inhibitors that decrease urate formation and uricase enzymes that catalyze the conversion to allantoin, a more soluble purine product.