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Related to uricosuric: Uricosuric agents, probenecid, pegloticase


Promoting the excretion of uric acid in the urine.

[From uric + uric.]


(Biology) increasing or promoting the excretion of uric acid in urine
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Adj.1.uricosuric - acting to increase the excretion of uric acid in the urine
References in periodicals archive ?
Angiotensin receptor blockers have a mild uricosuric effect and may help with lowering uric acid levels.
Members of the Food and Drug Administration's Arthritis Advisory Committee have voted in favor of recommending approval of the investigational uricosuric drug lesinurad at 200 mg daily for the proposed indication of treatment of hyperuricemia associated with gout in combination with a xanthine oxidase inhibitor, such as allopurinol or febuxostat.
1 Targeting Patients with Refractory Gout - Novel Uricosuric Drugs as Add-On Therapy 111 7.
The cornerstone of the clinical management of gout is anti-hyperuricemic therapy, either by uricosuric drugs or by XO inhibitors (XOI), such as allopurinol [5].
The uricosuric agent probenecid was recognized as an alternative first-line agent for urate lowering in patients who could not tolerate or had a contraindication to at least one xanthine oxidase inhibitor.
A sixth agent, sulfinpyrazone (Anturane), a uricosuric agent, has been withdrawn from the market, but there are no reports describing its use to treat gout in pregnant women.
In patients in whom allopurinol toxicity occurs, options include other xanthine oxidase inhibitors (febuxostat), a uricosuric agent (probenecid), or allopurinol desensitisation (only in cases of mild rash).
As is known, salicylic acid is uricosuric at doses over 4-5 g/day, whereas lower doses can cause hyperuricemia via urate retention (20,21).
Evaluation of diuretic, saluretic and uricosuric actions of the tinctures and saponins from Anthemis tinctoria L.
Prospective randomized studies targeting uric acid reduction with allopurinol or uricosuric agents are necessary to finish the controversy of the atherogenity of uric acid.