uricosuric agents


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Related to uricosuric agents: allopurinol, xanthine oxidase inhibitors

uricosuric agents

Used to reduce the uric acid in the body, and thus to treat gout.
References in periodicals archive ?
Aggrenox [R] (aspirin/extended-release dipryidamole) Potential Drug Interactions The following medications are known to have the potential to interact with aspirin: ACE inhibitors, acetazolamide, anticoagulants, anticonvulsants, beta blockers, diuretics, methotrexate, NSAIDs, and oral hypoglycemic and uricosuric agents.
12) URAT1 blockade is now appreciated to be the mechanism of several currently-prescribed uricosuric agents, including probenecid.
Uricosuric agents, such a probenecid, and the xanthine oxidase inhibitor allopurinol are used for this purpose.
Fortunately, novel, effective antihyperuricemics are in clinical development to counter the limitations of allopurinol and uricosuric agents.
Some guidelines use uric acid excretion rates to help with that choice: A xanthine oxidase inhibitor, such as allopurinol, is recommended for those excreting more than 800 mg/24 hr, and uricosuric agents are recommended for those with lower rates.