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urokinase

   Also found in: Medical, Acronyms, Encyclopedia, Wikipedia 0.01 sec.
u·ro·ki·nase  (yr-kns, -nz)
n.
An enzyme in human urine that catalyzes the conversion of plasminogen to plasmin and is used in medicine to dissolve blood clots.
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.urokinase - protease produced in the kidney that converts plasminogen to plasmin and so initiates fibrinolysis
peptidase, protease, proteinase, proteolytic enzyme - any enzyme that catalyzes the splitting of proteins into smaller peptide fractions and amino acids by a process known as proteolysis


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With the advent of thrombolytic agents such as urokinase and recombinant tissue plasminogen activator (tPA), a series of promising experimental and clinical studies began to demonstrate the therapeutic benefit of intraventricular administration of fibrinolytic agents for the treatment of IVH.
ID=6671 Alicia Ault, 'US FDA again stops urokinase sales', The Lancet, Vol 354, 24 July 1999.
Improved financial performance is providing the company with the increased flexibility it needs to shape a suitable distribution agreement for its urokinase product line.
 
 
 
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