valproate

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val·pro·ate

 (văl-prō′āt)
n.
A salt or ester of valproic acid, especially the sodium form, which is used as an anticonvulsant.

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Sannita, "Study of bioequivalence of magnesium and sodium valproates," Journal of Pharmaceutical and Biomedical Analysis, vol.
Magnesium valproate is chemically known as magnesium 2-propylpentanoate.
Rajkot, India) has provided magnesium valproate and its process related impurities working standards and samples.
The resolution between the 2-(1-ethyl-methyl)pentanoic acid and the valproate salt was not achieved by the other columns.
Magnesium valproate and its related impurities working standard solution containing 200 [micro]g/mL were prepared in a 100 mL volumetric flask by dissolving 20.
Magnesium valproate and its related impurities sample (different batch) solution containing 200 [micro]g/mL were prepared in a 100 mL volumetric flask by dissolving 20 mg each in 25 mL acetonitrile: water (50:50) and then diluting to volume with the same diluent.
Method for the determination of magnesium valproate and its related impurities in bulk drug is further validated as per ICH Q2(R1) guideline [21].
The working standard of magnesium valproate and its related impurities were added to the samples and the recovery was calculated which was between 98 and 102%; these were well within the acceptance criteria.
Six different preparations of the same magnesium valproate and its related impurities sample, each 0.
The linearity of the method was evaluated by analyzing eight solutions in the concentration ranges 50-350 [micro]g/mL for each solution of magnesium valproate and its related impurities.