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vinca alkaloid

   Also found in: Medical, Wikipedia 0.01 sec.
vinca alkaloid
n
(Medicine / Pharmacology) Med any of a group of alkaloids obtained from the periwinkle Vinca rosea, such as vinblastine and vincristine, that interfere with cell division and are used in the treatment of cancer


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The cancer itself, which can obstruct the bowel, affect the autonomic nervous system, or cause spinal cord compression * Disease effects resulting from illness such as dehydration, spinal cord compression, immobility, or changes in bowel habits * Previous laxative abuse * Cancer therapies such as vinca alkaloids * Other interventions for symptom management such as opioids or tricyclic antidepressants Prevention and management should be essential components of nursing practice.
In contrast to other clinical useful antimicrotubules agents such as the vinca alkaloids and colchicines, which induce net disassembly by microtubules, paclitaxel shifts the equilibrium towards microtubule assembly.
Suspect Drugs Chemotherapy Agents Associated With Neurotoxicity Combination of methotrexate*, cyclophosphamide, and fluorouracil* Vinca alkaloids Cytarabine Platinum analogues Ifosfamide Taxol Taxotere Fludarabine Suramin Agents Associated With Occasional Reports of Cognitive or Motor Impairment L-asparagine Busulfan Hexamethylmelamine Procarbazine Thiotepa *Also associated with cognitive impairment individually.
 
 
 
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