xeroderma


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Related to xeroderma: ichthyosis

xer·o·der·ma

 (zîr′ō-dûr′mə) also xe·ro·der·mi·a (-mē-ə)
n.
Excessive or abnormal dryness of the skin, as in ichthyosis.

xeroderma

(ˌzɪərəʊˈdɜːmə) or

xerodermia

n
1. (Pathology) any abnormal dryness of the skin as the result of diminished secretions from the sweat or sebaceous glands
2. (Pathology) another name for ichthyosis
xerodermatic, ˌxeroˈdermatous, xerodermic adj
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.xeroderma - a mild form of ichthyosis characterized by abnormal dryness and roughness of the skin
ichthyosis - any of several congenital diseases in which the skin is dry and scaly like a fish
xeroderma pigmentosum - a rare genetic condition characterized by an eruption of exposed skin occurring in childhood and photosensitivity with severe sunburn; inherited as a recessive autosomal trait in which DNA repair processes are defective so they are more likely to chromosome breaks and cancers when exposed to ultraviolet light
Translations

xe·ro·der·ma

, xerodermia
n. xeroderma, piel excesivamente seca.
References in periodicals archive ?
Strong sun-cream and clothing helped at first but after he suffered further serious burns in 2013 tests revealed Leo had xeroderma pigmentosum (XP), which leaves his skin Dna unable to repair damage caused by ultraviolet (UV) light.
Jusqu'a l'age de la puberte, la peau des enfants et des adolescents est plus fine et son systeme pigmentaire encore immature, cela la rend donc particulierement vulnerable aux effets cancerigenes des rayonnements UV, au meme titre que les personnes ayant des antecedents familiaux de cancer de la peau ou des troubles genetiques, tels que ceux pigmentaire ou xeroderma, ainsi que les personnes avec des troubles de l'immunite (maladies affectant le systeme immunitaire).
beaucoup moins que] Il est tres difficile de vivre en Algerie avec un enfant ayant la pathologie d'atteinte de xeroderma pigmentosum [beaucoup plus grand que].
And well done to his mum Nicola who has written a story to help him - and other kids - to understand his condition, xeroderma pigmentosum.
In terms of the cellular NER, excision repair crosscomplementation group 1 (ERCC1) nuclease forms a heterodimer with exicision repair cross-complemenentation group 4 (ERCC4, also known as xeroderma pigmentosum, complementation group F) and accomplishes repair of bulky DNA-platinum adducts (6-8).
Thiol status and cytopathological effects of acrolein in normal and xeroderma pigmentosum skin fibroblasts.
Several investigators subsequently established that humans suffering from the rare autosomal recessive disease xeroderma pigmentosum (XP) are defective in NER and consequently suffer an enormously increased risk of developing skin cancer following exposure to sunlight.
The variant form of human syndrome Xeroderma Pigmentosum (XP-V) is caused by mutations in DNA polymerase (hpoln).
By adopting this strategy they have succeeded in identifying pathogenic mutations responsible for this disease in the ERCC4 gene, which had already been linked to two other rare diseases: xeroderma pigmentosum and a type of progeria.
Dorey and Yolanda Nez are a married Navajo couple who bear an unjust burden: their daughter (Leanndra, 16) and her younger brother (who passed away at age 11) were both born with Xeroderma Pigmentosum, also known as XP.
His skin had normal turgor, but he had xeroderma and a few keratotic lesions; he had dry mucous membranes.
Therapeutic inhibition of DNA repair in cancer cells can sensitize the cancer cells towards the chemotherapeutics or else they can function as synthetic lethal approach for treatment of cancers with DNA repair defects such as Nucleotide Excision Repair (NER) of Xeroderma pigmentosum.