zebrafish


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ze·bra·fish

or zebra fish (zē′brə-fĭsh)
n. pl. zebrafish or ze·bra·fish·es or zebra fish or zebra fish·es
A small freshwater fish (Danio rerio) of South Asia that has horizontal dark blue and silvery stripes, is popular in home aquariums, and is used as a model organism in the study of developmental biology and medical genetics. Also called zebra danio.

zebrafish

(ˈzɛbrəˌfɪʃ)
n
(Animals) an Indian tropical fish with dark blue and silvery stripes

ze•bra•fish

(ˈzi brəˌfɪʃ; Brit. also ˈzɛb rə-)

n., pl. -fish•es, (esp. collectively) -fish.
a thin freshwater minnow, Brachydaniorerio, of India, having luminous blue and gold horizontal stripes.
[1765–75]
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In the last 10 to 15 years, as regenerative organisms like zebrafish have become genetically tractable to study in the lab, I became convinced that these animals might be able to teach us what is possible for human regeneration, Pomerantz said.
When the researchers treated zebrafish with a morpholino that targets the egfl7 gene, the fish developed blood vessel defects.
The compounds, known as epoxyeicosatrienoic acids, or EETs, boosted stem cell engraftment in both zebrafish and mice and could make human bone marrow transplant more efficient.
For the first time, the researchers reveal how this niche forms, using time-lapse imaging of naturally transparent zebrafish embryos and a genetic trick that tagged the stem cells green.
Professor Brunhilde Wirth, Head of the Institute of Human Genetics, University of Cologne, Germany, said that in most of their recent research, they have started out by using zebrafish embryos in which PLS3 was knocked-out and studying their development at the three and five day-old stage.
Previously, we developed transgenic zebrafish that specifically report ER transcriptional activity in all tissues of embryos and larvae with single cell resolution (Gorelick and Halpern 2011).
It has previously been shown that zebrafish are able to discriminate between colors, even some not recognized by other commonly used laboratory animals.
explained that zebrafish were increasingly being used in place of rodents to screen drugs for rare genetic disorders.
The Edinburgh University team studied zebrafish because they share more than 80% of the genes associated with human diseases.
Zebrafish are ideal for studying the early stages of disease development, including MS.
Squid and zebrafish can both change colour to attract mates and to frighten off predators.
The morphological and molecular basisof tissue and organ development in zebrafish embryos resembles that of humans, and the overall drug toxicity is also comparable with that observed in animals.