zidovudine


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Related to zidovudine: stavudine, didanosine

zi·do·vu·dine

 (zĭ-dō′vyo͞o-dēn′)
n. Abbr. ZDV
See AZT.

[Alteration and blend of azidothymidine and edoxudine, an antiviral drug having a similar structure (e(thyl) + d(e)ox(y)- + u(ri)dine), with -v- perhaps from antiviral.]

zidovudine

(zaɪˈdɒvjʊˌdiːn)
n
(Pharmacology) a drug that is used to treat AIDS. Also called: AZT

zi•do•vu•dine

(zaɪˈdoʊ vyuˌdin)

n.
the international generic term for azidothymidine. Compare AZT.
[1986; of undetermined orig.]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.zidovudine - an antiviral drug (trade name Retrovir) used in the treatment of AIDSzidovudine - an antiviral drug (trade name Retrovir) used in the treatment of AIDS; adverse side effects include liver damage and suppression of the bone marrow
NRTI, nucleoside reverse transcriptase inhibitor - an antiviral drug used against HIV; is incorporated into the DNA of the virus and stops the building process; results in incomplete DNA that cannot create a new virus; often used in combination with other drugs
Translations

zidovudine

n zidovudina
References in periodicals archive ?
21, 2015 /PRNewswire-iReach/ -- The 'Global and Chinese Zidovudine Industry, 2010-2020 Market Research Report' is a professional and in-depth study on the current state of the global Zidovudine industry with a focus on the Chinese market.
Infants received single-dose nevirapine and four weeks of zidovudine.
This study reveals a very high incidence of anaemia supposedly related to zidovudine as haemoglobin levels rose after stopping zidovudine.
They considered only antepartum treatment, divided into four categories: none, zidovudine monotherapy, dual therapy and HAART.
Extended prophylaxis with nevirapine or with nevirapine and zidovudine for the first 14 weeks of life significantly reduced postnatal HIV-1 infection in 9-month-old infants.
The reporting rate for adequate zidovudine in 2004 was 94%, which indicates the proportion of HIV-positive women for whom information was actually recorded regarding administration of zidovudine.
3] during or after delivery were offered combination antiretroviral therapy with nevirapine, zidovudine, and lamivudine.
Roy Gulick and a multicenter team report the longest patient follow-up to date showing that the simultaneous initiation of indinavir (Crixivan), zidovudine (Retrovir, AZT), and lamivudine (Epivir, 3TC) therapy is superior to sequential initiation (JAMA).
The researchers administered two daily antiviral drugs, zidovudine and lamivudine.
The preferred regimen based on protease inhibitors (PIs) calls for a combination of lopinavir/ritonavir (co-formulated as Kaletra) together with lamivudine and either zidovudine or stavudine.
The package insert for zidovudine states that "concomitant use of zidovudine with stavudine should be avoided since an antagonistic relationship has been demonstrated in vitro.
In vivo antagonism with zidovudine plus stavudine combination therapy.