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The genetic condition of a zygote, especially with respect to its being a homozygote or a heterozygote.


(Genetics) genetics the similarity or differences between DNA sequences on the chromosomes of a fertilized egg


(zaɪˈgɒs ɪ ti, zɪ-)

1. the characterization of a hereditary trait in an individual according to whether the gene pairs for the trait are homozygous or heterozygous.
2. the characterization of twins, triplets, etc., according to whether they are monozygotic or dizygotic.
[1945–50; probably derivative of -zygous (see heterozygous), on the model of viscous: viscosity, etc.]
References in periodicals archive ?
A standard physical resemblance questionnaire diagnoses the zygosity of the twins (Nichols and Bilbro, 1966).
This additional view provides a bird's eye picture of all published disease-causing variants juxtaposed on the various gene transcripts, allowing users to quickly spot patterns of pathogenicity or zygosity in different transcripts and at different gene loci.
Amyloid-related imaging abnormalities with edema occurred in up to 27% of APOE-epsilon-4 carriers, depending on their zygosity It also appeared in up to 14% of noncarriers; the relationship was dose dependent.
Amyloid-related imaging abnormalities with edema (an adverse event associated with immune response directed toward plaques) occurred in up to 27% of APOE-ep-silon-4 carriers, depending on their zygosity.
This method allows twin zygosity to be successfully verified and facilitates an estimate of whether there is adequate fetal DNA present per fetus.
Since Twin A refused zygosity testing, the counsellor could say that her HD result might not strictly apply to her sister, and that if her sister ever wanted to know her own status, she would have to go through the predictive testing process herself.
Variant calling is the step wherein nucleotides in aligned sequence reads are used to infer the presence and zygosity of variants.
Questionnaires provided additional information on multiple births including number of babies delivered from the index pregnancy, sex of multiple birth sibling(s), and zygosity based on the participant's perception and test results when available.
DNA tests by the center can be used to analyze siblingship, establish cousin or grandparent relationships and determine twin zygosity.
A likely explanation is that since most clinic labs have either no method or only unreliable methods of identifying sickle hemoglobin and none of the methods described here can determine zygosity, patients are less aware of the condition and probably die before seeking medical attention.
The zygosity of the participating pairs was determined by the genotyping of ten highly polymorphic genetic markers.