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Related to zymogen: zymogen granules




(Biochemistry) biochem any of a group of compounds that are inactive precursors of enzymes and are activated by a kinase


(ˈzaɪ mə dʒən, -ˌdʒɛn)

any of various enzyme precursor molecules that may change into an enzyme as a result of catalytic change. Also called proenzyme.
[< German (1875); see zymo-, -gen]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.zymogen - any of a group of compounds that are inactive precursors of enzymes and require some change (such as the hydrolysis of a fragment that masks an active enzyme) to become active
organic compound - any compound of carbon and another element or a radical
References in periodicals archive ?
Trypsinogen, like all other zymogens, is packaged in zymogen granules, which further retard trypsinogen activation.
The Inactive enzymes, or proenzymes, contained in pancreatic zymogen granules are listed below along with the specific substances theey digest when activated.
As a key enzyme in the melanization cascade, PO is usually synthesized and released into the hemolymph as the inactive zymogen prophenoloxidase (proPO).
Plasminogen which is involved in the fibrinolytis system is present in the tissue as zymogen and is activated as a result of interaction with tissue plasminogen activator (t-PA) which is also present in the tissue.
Autoantibodies to zymogen granule glycoprotein 2 (GP2) have shown specificity for Crohn's disease and could improve the serological diagnosis of IBD.
Acinic cell carcinoma (AcCC) is a malignant epithelial salivary gland neoplasm that demonstrates serous acinar cell differentiation with cytoplasmic zymogen secretory granules.
com)-- Plasminogen activator (PA), classified immunological into urokinase-type PA (uPA) and tissue-type PA (tPA), converts the zymogen plasminogen to the active, broad-spectrum serine protease plasmin.
Activated factor XII levels are dependent on factor XII 46C/T genotypes and factor XII zymogen levels, and are associated with vascular risk factors in patients and healthy subjects.
MMP-1 is secreted from cells as an inactive precursor of the active proteinase, zymogen (Pardo and Selman 2005).
Measurement of the size distribution of zymogen granules from rat pancreas.
The protein is produced in the liver as a zymogen and becomes activated upon propeptide cleavage.