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 (kăl′sĭ-trī′ôl′, -ōl′)
The active metabolite of vitamin D, C27H44O3, that is synthesized in the kidneys and liver from vitamin D2 or vitamin D3 and acts as a calcium-regulating hormone. A synthetic form is used as a drug to treat hypocalcemia, bone disease caused by renal failure, and, in topical preparations, psoriasis.

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


n calcitriol m
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References in periodicals archive ?
Aberrant calcium metabolism is related to sarcoidosis and other granulomatous disorders as a result of increased levels of active 1,25-dihydroxy vitamin D (OHD).
Instead, it is also proposed that increased formation of vitamin D metabolite 1,25-dihydroxy vitamin D may have negative feedback on the hepatic synthesis of vitamin D.5 It is also found that in obesity there is increased metabolic clearance of vitamin D especially in women, may be because of increased uptake by adipose tissue.6 Prevalence of obesity was higher among women as compared to men (33.5% vs 24.1%).
Furthermore, cathelicidin expression is strongly stimulated by 1,25-dihydroxy vitamin D in epithelial cells, macrophages/monocytes, and neutrophils (11).
[27], that the synthesis of 25(OH)D in the liver is negatively inhibited by increasing level of 1,25-dihydroxy vitamin D.
Application-based segmentation and analysis of - 25-Hydroxy vitamin D tests & 1,25-Dihydroxy vitamin D test