Plumbagin, a medicinal plant (Plumbago zeylanica)-derived 1,4-naphthoquinone
, inhibits growth and metastasisof human prostate cancer PC3M-luciferase cells in anorthotopic xenograft mouse model.
"Dependence of antitumor activity on the electrophilicity of 2-substituted 1,4-naphthoquinone
derivatives", Bull Korean Chem Soc 2007; 28(4): 691-694.
Keywords: Acrylates, Azomethineylide, 1,4-Naphthoquinone
, Ninhydrin, Proline, Pyrrolizidine.
Lawsone (2-hydroxy, 1,4-naphthoquinone
) is represented by the hydroxyl group.
Galembeck, "Gas-phase dissociation of 1,4-naphthoquinone
derivative anions by electrospray ionization tandem mass spectrometry," Journal of Mass Spectrometry, vol.
, a pro-oxidant, ameliorated radiation induced gastro-intestinal injury through perturbation of cellular redox and activation of Nrf2 pathway," Drug Discoveries & Therapeutics, vol.
Antitrypanosomal activities and cytotoxicity of some novel imido-substituted 1,4-naphthoquinone
(2002) observed the formation of 6-hydroxy 1,4-naphthoquinone
at pH 12, whereas Piram et al.
Protein targets of 1,4-benzoquinone and 1,4-naphthoquinone
in human bronchial epithelial cells.
While 2-tridecanone made up about 20% of the secretion of both sironids, it comprised 50% in the stylocellid; 1,4-naphthoquinone
and 6-methyl-1,4-naphthoquinone were found in very small amounts in the stylocellid, but at values from about 12% to nearly 18% in the sironids; pentadecan-2-one was at 13.8% for the stylocellid, butless than1.7% for the sironids, and so on.
Viana et al., "In vitro and in vivo leishmanicidal activity of 2-hydroxy-3-(3methyl-2-butenyl)- 1,4-naphthoquinone
(lapachol)," Phytotherapy Research, vol.