isotretinoin

(redirected from 13-cis retinoic acid)
Also found in: Medical.

i·so·tre·ti·noin

 (ī′sō-trĕt′n-oin′)
n.
A synthetic isomer of retinoic acid that inhibits sebaceous gland secretion and is used in the treatment of severe nodular acne. It can cause birth defects if taken during pregnancy.

[iso- + tretinoin, retinoic acid (t(rans)- + retino(ic acid) + -in).]

isotretinoin

(ˌaɪsəʊtrəˈtɪnəʊɪn)
n
(Pharmacology) a drug related to vitamin A, used to treat severe acne that has failed to respond to other treatment
Translations

isotretinoin

n isotretinoína
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References in periodicals archive ?
Randomized trial of 13-cis retinoic acid compared with retinylpalmitate with or without beta-carotene in oral premalignancy.
Conclusion: 13-cis Retinoic acid has not shown a significant role in the reversal of tamoxifen induced changes in the uterine tissue after a short term administration of three months.
With the pioneering 13-CIS Retinoic Acid Treatment, Ryan is now into his fourth month of being disease free.
The treatment of severe cystic acne with 13-cis retinoic acid.
The most efficacious acne treatment, 13-cis retinoic acid (RA) or Roaccutane[R], is well known for causing considerable improvement in very severe acne conditions (for example acne conglobata) but usage is also limited by its potential teratogenic effects.
Preliminary results with radioprotectors such as amifostine [64] and glutamine [65] and chemopreventive agents such as 13-cis retinoic acid [66,67] and interferon alfa [66,67] have also been encouraging.
In an NCI study, persons with large numbers of skin tumors were fed a vitamin A-related compound, called 13-cis retinoic acid.