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Adj.1.165 - being five more than one hundred sixty
cardinal - being or denoting a numerical quantity but not order; "cardinal numbers"
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Tabbernee (Phillips Theological Seminary) fully describes the reasons for ecclesiastical opposition and the Church's charges from the inception of the cult in 165 AD to 324 AD, the opposition of the Roman empire and the resulting persecution, and the redoubled opposition of Church and state through 550 AD.