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Noun1.3TC - a nucleoside reverse transcriptase inhibitor that is very effective in combination with zidovudine in treating AIDS and HIV3TC - a nucleoside reverse transcriptase inhibitor that is very effective in combination with zidovudine in treating AIDS and HIV
NRTI, nucleoside reverse transcriptase inhibitor - an antiviral drug used against HIV; is incorporated into the DNA of the virus and stops the building process; results in incomplete DNA that cannot create a new virus; often used in combination with other drugs
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References in periodicals archive ?
In these studies, DTG + 3TC demonstrated non-inferiority based on plasma HIV-1 RNA <50 copies per milliliter (c/mL), a standard measure of HIV-1 control, at Week 48 when compared to a three-drug regimen of DTG and two nucleoside reverse transcriptase inhibitors (NRTIs), tenofovir disoproxil fumarate/emtricitabine (TDF/FTC), in treatment-naive, HIV-1 infected adults.
DTG plus 3TC may also be considered as an alternative combination where other NRTIs cannot be used (4, 5).
There was neither difference in the frequency of NNRTI and PI (p = 0.40) as third drug nor AZT+ 3TC and TDF + 3TC (p = 0.56) as backbones.
"Alongside 3TC and other project partners, our team is deeply committed to delivering this state-of-the-art system that supports economic growth and accessibility for dozens of communities along this impacted corridor and across the entire region."
Depending on age, availability and as per WHO recommendations at the time of diagnosis, a combination of the two NRTIs (ZDV and 3TC) plus either NNRTI (nevaripine) or the PI (nelfinavir) was used to initiate therapy.
The combination of ZDV + 3TC + NFV was the most modified of all combinations (30.0%), while the combination of ZDC + 3TC + EFV was the most common ART regimen switched to (21.3%), followed by AZT + 3TC + LPV/r (13.9%).
This was a one-arm cohort study to evaluate the efficacy and safety of TDF, 3TC, and EFV in antiretroviral-naive Chinese adults with HIV/HBV co-infection (ClinicalTrials.gov, NCT01751555).
COMMUNITY SPIRIT This community-minded attitude is shown in the businesses that choose to open in Crosby and Waterloo: from the entrepreneurs behind Coffee & The Tea Leaf who are bringing together the very best in local independents, such as The Sugar Tree, creators of naturally flavoured sweet and savoury sugars; to the charity running 3tc to make the community a more technologicallysound place.
The initial therapy in most of the subjects was zidovudine (AZT)+lamivudine (3TC)+nevirapine (NVP).
(c) ART regimen: AZT = zidovudine; 3TC = lamivudine; EFV = efavirenz; NVP = nevirapine; d4T = stavudine; TDF = tenofovir.