For the development of molecular diagnostic platforms, polymeric films are derived from hydroxyphenylacetic acid [16, 17], 4-aminophenol
[5, 18], 3-aminophenol , and 4-aminothiophenol .
The 4-hydroxylation of aniline hydrochloride results in the formation of 4-aminophenol
, which is determined spectorphotometrically by indophenol reaction.
Wang and coworkers reported the preparation of CdS quantum dot/graphene/MIP-based electrochemical sensor for selective recognition of 4-aminophenol
in water samples .
In Figure 11, the UV-Vis absorption spectra revealed that the addition of AgNPs induced the lowering of peak intensity at 400 nm and the appearance of a new absorption peak at 293 nm indicating the formation of 4-aminophenol
. Finally, the formation of 4-AP is confirmed by the UV-Visible spectrum of pure 4-AP, which shows similar absorption peaks to that of an authentic sample.
EPSs have also been used in the synthesis of other metal nanoparticles, such is the case of xanthan gum, that has been used as a reducing and stabilizing agent to produce palladium nanoparticles (Pd-NPs) with very good catalytic activity during the reduction of 4-nitrophenol to 4-aminophenol
by sodium borohydride .
, 4-chloroaniline, or 4-aminobenzenesulfonamide (50 mmol) was added to a solution of compound 7 (1.56 g, 50 mmol), in DMF (10 mL) containing few drops of 37% hydrochloric acid, and the mixture was heated under reflux for 10 hours.
Vander Heyden, "Validation of a fluorimetric assay for 4-aminophenol
in paracetamol formulations," Talanta, vol.
AH was measured using 4-hydroxylation of aniline to 4-aminophenol
(Cohen et al.
This was caused by diaminotoluene and diaminobenzene or cross- reactions of PPD with para-amino compounds (benzocaine, sulfa drugs, aminoazobenzene, IPPD, PABA) and hairdressing allergens (2,5- diaminotoluene sulfate, 2-nitro-4- phenylenediamine, 4-aminophenol
, 3- aminophenol).37,39The clinical manifestations of allergic contact dermatitis varies in severity from an intensely itchy erythematous with patches of painful, itchy exudative bullous eruptions.37-42The patch test is the gold standard method for diagnosis of allergic contact dermatitis from henna, while the prevalence of the positive patch test in pure henna is 3%, and the prevalence of the patch test positivity to henna with PPD is 35% or more.43,44
A solution of furan-2-carbaldehyde (2 g, 20.3 mmol) was dissolved in dried diethyl ether (15 mL) and was added to a solution of 4-aminophenol
(2.3 g, 20.3 mmol) which was already dissolved in dried diethyl ether (90 mL).
Influence of pH, temperature and glucose on biodegradation of 4-aminophenol
by a novel bacterial strain, Pseudomonas sp.
considerable toxicity exerts 4-aminophenol
. This compound causes skin and eye irritation, eczemas, asthma and anoxia .