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An unsaturated androgenic steroid, C19H26O2, that is secreted by the testis, ovary, and adrenal cortex and is a precursor of both androgens and estrogens. Until 2005, when its nonprescription sale and use became illegal in the United States, synthetic androstenedione was used as a dietary supplement to enhance athletic performance.

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
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The 17,20-lyase activity subsequently converts these steroids to dehydroepiandrosterone (DHEA) and 4-androstenedione [10].
Poor therapy control with elevated serum 4-androstenedione levels (>10 nmol/L) was observed in no patients at baseline (0%) and in only one patient (5.9%) at follow-up, whereas elevated levels of 17-OHP in serum (>36 nmol/L) were present in 4 patients (23.5%) at baseline and 2 patients at follow-up (11.8%).
4-Androstenedione and atrazine showed consistent undetectable activity in at least two assays.