bromouracil

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bromouracil

(ˌbrəʊməʊˈjʊərəsɪl)
n
a brominated derivative of uracil with antimetabolite properties
References in periodicals archive ?
8) The covalent SELEX or cross-linking SELEX or Photo-SELEX uses a RNA library with uracil analogs (5-iodouracil (5-IU) or 5-bromouracil (5-BrU)) to select aptamers with high affinity and specificity that can be UV-cross-linked to the target protein for biochemical and structural studies of nucleic acid-protein interactions and therapeutic applications.
6-TG (2-amino-6-mercaptopurine), 5-bromouracil (5-BU), D,L-dithiothreitol (DTT), PMA, and Hanks' balanced salt solution (HBSS) were purchased from Sigma; isoamyl alcohol was from J.
Modified libraries containing 5-bromouracil and 5-iodouracil residues have been used to generate photo-cross-linkable aptamers [Golden et al.