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 (flo͝or′ō-yo͝or′ə-sĭl, flôr′-)
An antineoplastic agent, C4H3FN2O2, used especially in the treatment of cancers of the skin, breast, and digestive system.


a chemotherapy drug used in the treatment of cancer, which operates by interfering with the abnormal growth of cells


(ˌflʊər əˈyʊər ə sɪl, ˌflɔr-, ˌfloʊr-)

a pyrimidine analog, C4H3FN2O2, used in the treatment of certain cancers.
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Noun1.fluorouracil - an antimetabolite used to treat certain cancers
antimetabolite - an antineoplastic drug that inhibits the utilization of a metabolite


n fluorouracilo
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References in periodicals archive ?
The chemotherapy consisted of 5-FU 400 mg slow IV push and 5-FU 1000 mg over 22 h.
The Committee calculated the ICER for Onivyde plus 5-FU and LV compared with 5-FU plus LV to be more than GBP100,000 per quality-adjusted life year (QALY), which is above what is considered value for money for the NHS.
While effective, 5-FU produces crusting and significant irritation, and is temporarily disfiguring, often affecting patient compliance with treatment.
Demehri and his coinvestigators randomly assigned 131 men and women who were at least 50 years old and who had at least four AKs on the face, scalp, and/or upper arms to apply 5% 5-FU cream mixed with either 0.
The existing treatment modalities including intralesional steroids, cryotherapy, silicone gel sheets, imiquimod, verapamil and high dose 5-FU have not shown to be very effective and there are only a few clinical studies using low dose 5-FU for keloids.
5-FU is an antimetabolite that is used in glaucoma filtration surgery and has been proposed as a putative anti-adhesive drug for use following tendon repair.
Editor's Note: Treatment with 5-FU and/or curcumin promoted disintegration of high-density tumor spheres, an effect that was greater in curcumin-treated co-cultures.
Over the past 20 years, increased understanding of the action mechanism of 5-FU has led to the development of combination strategies to increase its anticancer activity (Ming et al.
It was hypothesised that 5-FU and 5-FU based chemotherapy regimens cause cardiotoxicities, especially bradycardia, in a number of Pakistani cancer patients Therefore, it had been planned to conduct a retrospective study in this regard to check the hypothesis.
She continued to experience angina despite discontinuation of 5-FU, so she was admitted to the coronary care unit (CCU).
bolus dose of 5-FU is 500-600 mg/m2 every 3-4 weeks or 425 mg/m2 on days 1-5 every 4 weeks and Continuous I.