reductase

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re·duc·tase

 (rĭ-dŭk′tās′, -tāz′)
n.
Any of various enzymes that catalyze the reduction of an organic compound.

reductase

(rɪˈdʌkteɪz)
n
(Biochemistry) any enzyme that catalyses a biochemical reduction reaction
[C20: from reduction + -ase]

re•duc•tase

(rɪˈdʌk teɪs, -teɪz)

n.
any enzyme acting as a reducing agent.
[1900–05]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.reductase - an enzyme that catalyses the biochemical reduction of some specified substance
5-hydroxy-3-methylglutaryl-coenzyme A reductase, HMG-CoA reductase - a liver enzyme that is responsible for producing cholesterol
enzyme - any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions
Translations
réductase
還元酵素

re·duc·tase

n. reductasa, enzima que actúa como catalítico en el proceso de reducción.
References in periodicals archive ?
Prostate cells, as well as hair follicles, also are sensitive to testosterone, but they respond to testosterone indirectly, after it has been converted to dihydrotestosterone (DHT) by an enzyme called 5-alpha reductase.
While there was possible benefit in adding a 5-alpha reductase inhibitor like finasteride to his existing medication regimen of tamsulosin 0.
This is regarding the interesting article "The Clinical Importance of 5-Alpha Reductase in Human Health and Pathology," by Alan McDaniel (Townsend Letter, June 2017.
Finasteride is a selective inhibitor of type-2 5-alpha reductase enzyme, preventing the conversion of testosterone to dihydrotestosterone (DHT).
The importance of DHT in prostatic growth is dramatically manifested in patients with congenital deficiency of 5-alpha reductase, the enzyme responsible for conversion of testosterone to DHT.
It inhibits type 2 5-alpha reductase enzyme so that testosterone conversion to dihydrotestosterone (DHT) will be blocked.
Although medical treatment of BPH with alpha blockers and 5-alpha reductase inhibitors may ameliorate the urinary symptoms, surgical intervention may be inevitable in some patients.
In one study, several other natural and synthetic polyphenolic compounds including anthrarobin were found to be effective inhibitor of type I 5-alpha reductase which is involved in production of benign prostatic hyperplastic and prostatic cancer [5].
Dihydrotestosterone, the active form of testosterone (Through action of 5-alpha reductase) is responsible for prostatic hyperplasia and 5-alpha reductase inhibitors provide base for medical treatment.
Gann suggested starting with compounds--especially dietary agents--that could inhibit 5-alpha reductase.
However, the 5-alpha reductase inhibitor trials provided proof of principle that the risk of a subset of prostate cancer can be reduced by drugs.
127) 5-alpha reductase is the enzyme that converts testosterone to DHT.

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