mesalamine

(redirected from 5-Aminosalicylic acid)
Also found in: Medical, Acronyms.

me·sal·a·mine

 (mə-săl′ə-mēn′)
n.
A salicylate drug derived from sulfasalazine, C7H7NO3, used primarily to treat inflammatory bowel disease.

Translations

mesalamine

(USAN), mesalazine (INN) n mesalamina, mesalazina (INN)
References in periodicals archive ?
Of additional interest will be whether the effect observed is related to the anti-inflammatory properties of 5-aminosalicylic acid and whether it provides additional evidence regarding colorectal cancer chemoprevention.
Mesavance consists of 5-aminosalicylic acid incorporated into a proprietary drug delivery system.
Drug AWC/Day* Dosage 5-AMINOSALICYLIC ACID AGENTS mesalamine No generic available 4.
It is estimated that 40% of patients receiving the recommended dose of 5-aminosalicylic acid continue to experience flares of disease activity.
Twenty patients with mild-to-moderate ulcerative colitis who had failed to respond adequately to 5-aminosalicylic acid and/or azathioprine were randomly assigned in a 4:1 ratio to receive, in double-blind fashion, adjunctive treatment with Polyphenon E (a green tea extract) or placebo for 8 weeks.
5-Aminosalicylic acid reverses endosulfan-induced testicular toxicity in male rats.
Another approach for increasing blood 6-TGN concentrations is the combination of 5-aminosalicylic acid (5-ASA) and thiopurine.
He had a diagnosis of ulcerative colitis and was treated with 5-aminosalicylic acid (5-ASA or mesalazine) 500 mg, six times a day (3g/day) for six years, with minimal or no improvement.
Some patients' symptoms will resolve spontaneously, whereas others may require over-the-counter antidiarrheal medications such as bismuth subsalicylate, or in other cases, 5-aminosalicylic acid compounds or immunosuppressants.
It is formed by sulphapyridine, which is readily absorbed, and 5-aminosalicylic acid (5-ASA), of which only 25% is absorbed and then excreted in urine as acetyl-5-ASA (9,17).
All patients were receiving concomitant therapy with 5-aminosalicylic acid derivatives (5-ASA) and/or immunomodulator medications.
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