Reliable markers for HCC diagnosis are aspartate transaminases (AST) and alanine transaminases (ALT) (Whittby et al., 1984), lactate dehydrogenase (LDH) (King, 1965), bilirubin (Harper, 1961), Gamma-glutamyl transferase (GGT) (Yao et al., 2004), alpha feto protein (Sell and Becker, 1978), 5-nucleotidase
(5NT) (Sadej et al., 2006), Glucose-6-phosphate dehydrogenase (G6PDH) (Molero et al., 1994) and albumin (Vandenberghe, 1996).
Scorpion venom contains a mixture of several low molecular weight basic proteins, neurotoxins, nucleotides, amino acids, oligopeptides, cardiotoxins, nephrotoxins, haemolytic toxins, phosphodiesterase, phospholipase A, hyaluronidase, acetylcholinesterase, glycosaminoglycans, histamine, serotonin, 5-hydroxyptamine and proteins that inhibit protease, angiotensinase, succinate-dehydrogenase, ribonuclease, and 5-nucleotidase
. Multiple toxins may be present in the venom of a single species which can produce a synergic effect in the victim .