566C80 - definition of 566C80 by The Free Dictionary
atovaquone (redirected from 566C80)
Also found in: Medical
A drug, C22H19ClO3, used to treat pneumonia caused by pneumocystis fungi and, in combination with proguanil, to prevent or treat malaria.
[Perhaps rearrangement of the letters of Aōt(us)
, night monkey genus on which testing was carried out during the development of atovaquone
; see a-1
+ ous, ōt-,
, ear (from the small external ears of night monkeys)
; see otic
) + (par)vaquone
, veterinary drug chemically related to atovaquone
, specific epithet of Theileria parva, apicomplexan cattle pathogen against which parvaquone is effective
, from Latin parva
, feminine of parvus
, small (from the relatively small size of the pathogen)
; see pau-
in Indo-European roots
) + qu(in)one
References in periodicals archive
Site of action of the antimalarial hydroxynaphtaquinone, 2-[trans-4-(4'-chlorophenyl) cyclohexyl]-3-hydroxy-1,4-naphthoquinone (566C80
Pudney, "Site of action of the antimalarial hydroxynaphthoquinone, 2-[trans-4-(4'-chlorophenyl) cyclo-hexyl]-3- hydroxy-1,4-naphthoquinone (566C80
)," Biochemical Pharmacology, vol.
Remarkable in vitro and in vivo activities of the hydroxynaphthoquinone 566C80
against tachyzoites and tissue cysts of Toxoplasma gondii.
The effect of atovaquone (566C80
) on the maturation and viability of Plasmodium falciparum gametocytes in vitro.
Remington, "Remarkable in vitro and in vivo activities of the hydroxynaphthoquinone 566C80
against tachyzoites and tissue cysts of Toxoplasma gondii," Antimicrobial Agents and Chemotherapy, vol.