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A stimulant, C7H7N4O2Cl, that is used to form a salt with certain pharmaceutical drugs, such as diphenhydramine.

[8-, conventional numbering of the position in the compound's purine ring to which the chlorine atom is attached + chloro- + theophylline.]
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Castro, "Optimization and validation of a method for the determination of caffeine, 8-chlorotheophylline and diphenhydramine by isocratic high-performance liquid chromatography.
For the measurement of caffeine concentrations by HPLC, 8-chlorotheophylline (internal standard) was added to the samples, and proteins in the samples were precipitated with acetonitrile.