(redirected from ABCC6)
Also found in: Thesaurus, Medical, Financial, Encyclopedia, Wikipedia.


A constellation in the Southern Hemisphere near the constellations Norma and Telescopium.

[Latin āra, altar, the constellation Ara; see as- in Indo-European roots.]


n, Latin genitive Arae (ˈɑːriː)
(Astronomy) a constellation in the S hemisphere near Scorpius
[from Latin: altar]


(in Britain) abbreviation for
Associate of the Royal Academy
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.Ara - a constellation in the southern hemisphere near Telescopium and Norma
2.Ara - macawsAra - macaws          
bird genus - a genus of birds
family Psittacidae, Psittacidae - coextensive with the order Psittaciformes
macaw - long-tailed brilliantly colored parrot of Central America and South America; among the largest and showiest of parrots
References in periodicals archive ?
Similarly, an additional mutation related to vascular calcification is present in ATP-binding cassette, subfamily C, member 6 ( ABCC6 ),[sup][58] a gene that codes for a transmembrane ATP-dependent protein.
Moreover, some ABC transporter genes, such as ABCB1, ABCA12, ABCA5, ABCA3, ABCC2, ABCC5, and ABCC6, were strongly upregulated in CTC-MCC-41 compared with HT-29 cells.
This is explained by the fact that DBA/2 mice have an alternative splice variant of the Abcc6 gene resulting in an increased susceptibility to develop tissue calcification [14-16].
The ATP-binding cassette subfamily C member 6 (ABCC6) gene was first reported in 2000 as the cause of PXE [3-5].
PXE is caused by mutations in the ABCC6 gene located on chromosome 16p13.1.4 This gene encodes MRP6, an adenosine-5"-triphosphate-binding cassette transmembrane transporter protein primarily expressed in the liver and the kidneys.
There are over 200 reported mutations of the PXE gene ABCC6, located on chromosome 16.
Piehler, "Copy number variations of the ATP-binding cassette transporter ABCC6 gene and its pseudogenes," BMC Research Notes, vol.
Boyd, "The distribution of Abcc6 in normal mouse tissues suggests multiple functions for this ABC transporter," Journal of Histochemistry and Cytochemistry, vol.
De los 17 genes restantes asociados al fenotipo HLFC contenidos en el modulo URFA, tres de ellos tienen funciones conocidas en el metabolismo lipidico (ABCC6, AKT2, HSD11B1) y uno mas que puede estar relacionado por su homologia con otra enzima (PNPLA4).
Acute myocardial infarction and a new ABCC6 mutation in a 16-year-old boy with pseudoxanthoma elasticum.
Katagiri and colleagues demonstrate in 20 patients with angioid streaks that ABCC6 variants play a significant role in affected Japanese individuals.
The mode of inheritance is autosomal recessive and responsible gene has been identified as adenosine triphosphate- binding cassette (ABC) subfamily C member 6 (ABCC6) gene, encoding multidrug resistant protein 6 (MDR6).1,2 Mutation in this gene causes progressive fragmentation and calcification of elastic tissue.