ACE inhibitor


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Related to ACE inhibitor: Angiotensin receptor blocker, Beta blockers

ACE inhibitor

 (ās)
n.
Any of a class of drugs that cause vasodilation and are used to treat hypertension and heart failure.

[a(ngiotensin) c(onverting) e(nzyme) inhibitor.]

ACE inhibitor

n
(Pharmacology) any one of a class of drugs, including captopril, enalapril, and ramipril, that cause the arteries to widen by preventing the synthesis of angiotensin: used to treat high blood pressure and heart failure
[C20: from a(ngiotensin-)c(onverting) e(nzyme) inhibitor]

ACE′ inhib`itor

(eɪs, ˈeɪˈsiˈi)
n.
any of a group of vasodilator drugs used in the treatment of hypertension and heart failure.
[1980–85; A(ngiotensin)-C(onverting) E(nzyme)]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.ACE inhibitor - an antihypertensive drug that blocks the formation of angiotensin II in the kidney, leading to relaxation of the arteriesACE inhibitor - an antihypertensive drug that blocks the formation of angiotensin II in the kidney, leading to relaxation of the arteries; promotes the excretion of salt and water by inhibiting the activity of the angiotensin converting enzyme; also used to treat congestive heart failure
antihypertensive, antihypertensive drug - a drug that reduces high blood pressure
Capoten, captopril - a drug (trade name Capoten) that blocks the formation of angiotensin in the kidneys resulting in vasodilation; used in the treatment of hypertension and congestive heart failure
enalapril, Vasotec - an ACE inhibitor (trade name Vasotec) that blocks the formation of angiotensin in the kidney and so results in vasodilation; administered after heart attacks
lisinopril, Prinival, Zestril - an ACE inhibiting drug (trade names Prinival or Zestril) administered as an antihypertensive and after heart attacks
Altace, ramipril - an ACE inhibitor (trade name Altace) used to treat high blood pressure or in some patients who have had a heart attack
Mavik, trandolapril - an ACE inhibiting drug (trade name Mavik) used in some patients after a heart attack or to treat hypertension
References in periodicals archive ?
Both the ACE inhibitor cough and angioedema appear to be caused by different amounts of another small protein called bradykinin.
All three were slightly but significantly better than a beta-blocker or ACE inhibitor in preventing stroke, Dr.
But the patients on an ACE inhibitor that crossed the blood-brain barrier accounted for almost all of that difference in decline.
A POEM in the February 2005 issue ("ARB no better than ACE inhibitor for prevention of nephropathy progression," J Fam Pract 2005; 54:108-109) discussed the head-to-head randomized double-blind trial from the New England Journal of Medicine by Barnett and colleagues, "Angiotensin-receptor blockade versus converting-enzyme inhibition in type 2 diabetes and nephropathy.
Conclusion: Left ventricular function evaluation and ACE inhibitor use were each associated with increased survival time in older Medicare beneficiaries with heart failure.
In the present study, 20 hypertensive subjects with normal renal function who were being treated with an ACE inhibitor or ARB were randomly assigned to consume a usual diet or a high-potassium diet, which was achieved by increasing intake of fruits and vegetables.
In normotensive patients with type 1 and type 2 diabetes, ACE inhibitor therapy reduces the risk of developing diabetic kidney disease, defined as new-onset microalbuminuria or macroalbuminuria, by 18% (strength of recommendation [SOR]: C, meta-analysis of randomized controlled trials [RCTs], disease-oriented evidence).
The PARADIGM-HF Trial, the largest heart failure trial ever conducted, showed that patients with HF-rEF who were given sacubitril/valsartan were more likely to be alive and less likely to have been hospitalized for sudden deterioration of their heart failure than those given the ACE inhibitor enalapril.
Yancy of Northwestern University in Chicago, recommend that the ARNI replace an ACE inhibitor or an angiotensin II receptor blocker (ARB) for patients who have been tolerating these therapies alongside standard care with a beta-blocker and, for some patients, an aldosterone antagonist as well.
The company stated that Entresto is usually administered along with other heart failure therapies in place of an ACE inhibitor or other angiotensin receptor blocker.
ARBs work by blocking the action of ACE, and may be prescribed if ACE inhibitor side effects are tiresome.
13) The diagnosis is made when a patient on an ACE inhibitor presents with nonpruritic, nontender, well-demarcated areas of angioedema and other causes have been ruled out.