ACE inhibitor

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ACE inhibitor

 (ās)
n.
Any of a class of drugs that cause vasodilation and are used to treat hypertension and heart failure.

[a(ngiotensin) c(onverting) e(nzyme) inhibitor.]

ACE inhibitor

n
(Pharmacology) any one of a class of drugs, including captopril, enalapril, and ramipril, that cause the arteries to widen by preventing the synthesis of angiotensin: used to treat high blood pressure and heart failure
[C20: from a(ngiotensin-)c(onverting) e(nzyme) inhibitor]

ACE′ inhib`itor

(eɪs, ˈeɪˈsiˈi)
n.
any of a group of vasodilator drugs used in the treatment of hypertension and heart failure.
[1980–85; A(ngiotensin)-C(onverting) E(nzyme)]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.ACE inhibitor - an antihypertensive drug that blocks the formation of angiotensin II in the kidney, leading to relaxation of the arteriesACE inhibitor - an antihypertensive drug that blocks the formation of angiotensin II in the kidney, leading to relaxation of the arteries; promotes the excretion of salt and water by inhibiting the activity of the angiotensin converting enzyme; also used to treat congestive heart failure
antihypertensive, antihypertensive drug - a drug that reduces high blood pressure
Capoten, captopril - a drug (trade name Capoten) that blocks the formation of angiotensin in the kidneys resulting in vasodilation; used in the treatment of hypertension and congestive heart failure
enalapril, Vasotec - an ACE inhibitor (trade name Vasotec) that blocks the formation of angiotensin in the kidney and so results in vasodilation; administered after heart attacks
lisinopril, Prinival, Zestril - an ACE inhibiting drug (trade names Prinival or Zestril) administered as an antihypertensive and after heart attacks
Altace, ramipril - an ACE inhibitor (trade name Altace) used to treat high blood pressure or in some patients who have had a heart attack
Mavik, trandolapril - an ACE inhibiting drug (trade name Mavik) used in some patients after a heart attack or to treat hypertension
References in periodicals archive ?
Of the 58 patients with systolic dysfunction, 45 (78%) were discharged with an ACE inhibitor prescription, seven (12%) had had a previous unsuccessful trial of ACE inhibition and two (3%) had aortic stenosis (a contraindication to use of ACE inhibitors).
Researchers are investigating whether combinations of calcium channel blockers and ACE inhibitors might be more effective than either treatment used alone.
Several large studies have indicated that ACE inhibitors improve survival among heart failure patients and may slow, or perhaps even prevent, the loss of heart pumping activity.
It is a once-daily tablet developed as an adjunctive treatment rather than a first-line therapy and is targeted to patients who don't respond to or are intolerant of such treatments as diuretics (with or without digitalis), to those who have not responded adequately to angiotensin converting enzyme (ACE) inhibitors or who cannot tolerate ACE inhibitors.
found that compared with other anti-hypertensive medications, such as beta blockers and diuretics, ACE inhibitors and ARBs were especially beneficial.
It was followed by a debate on usefulness and efficacy of ACE Inhibitors vs.
These interactions included angiotensin-converting enzyme (ACE) inhibitors and potassium-sparing diuretics; ACE inhibitors or angiotensin receptor blockers and sulfamethoxazole/trimethoprim (SMX/ TMP); benzodiazepines or zolpidem and other medications; calcium channel blockers and macrolide antibiotics; digoxin and macrolide antibiotics; lithium and loop diuretics or ACE inhibitors; phenytoin and SMX/TMP; sulfonylureas and antimicrobial agents; theophylline and ciprofloxacin; and warfarin and antimicrobial agents or non-steroidal antiinflammatory drags.
If ACE inhibitors can be shown to be beneficial in both of these extremely common diseases, management would be considerably simplified, observed Dr.
ACE inhibitors were not found more likely than other antihypertensive drugs to be associated with an increase in congenital heart defects when used in the first trimester only.
The study included 32,312 participants, age 65 and older, and sought to determine the safety of combination therapy of ACE inhibitors and ARBs in the clinical setting, as some randomized trials indicate an increased risk of kidney failure.
This study, by researchers from the University of Alberta and the University of Calgary, sought to determine the safety of combination therapy of ACE inhibitors and ARB in the clinical setting as some randomized trials indicate an increased risk of kidney failure.
ACE inhibitors are known to reduce cardiovascular morbidity and mortality, as well as proteinuria in patients with vascular disease or diabetes, whether or not they have heart failure?