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Related to ADIPOQ: Adiponectin, Resistin


A polypeptide hormone that is secreted by fat cells and regulates glucose and lipid metabolism, especially by increasing insulin sensitivity and muscle uptake of glucose and by decreasing glucose production in the liver.

[Latin adeps, adip-, fat + Latin nectere, to bind; see ned- in Indo-European roots + -in.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
References in periodicals archive ?
A recent meta--analysis (9) focused on adipokine profiles (ADIPOQ, LEP and RETN) as biomarkers in the gingival crevicular fluid (GCF) of obese and non-obese CP patients.
Indeed, these rats showed altered WAT (parametrial tissue-pad) functionality, such as enlarged pad mass, replete of large (insulin-resistant) adipocytes and containing very low ADIPOQ protein [34].
To validate the results of differentially expressed genes in transcriptome sequencing, leptin (Lep), ghrelin (Ghr), insulin-like growth factor 1 (Igf1), and adinopectin (Adipoq) genes were selected because they were differentially expressed in each diet group.
A selected gene panel from the genes identified by microarray analysis data based on their involvement in adipogenesis-related processes, including AdipoQ, AP2, PPAR[gamma]2, CEBP[alpha], CNTFR, LPL, LIPE, ACACB, and PCK1, was chosen for validation using qRT-PCR (Figure 2(c)).
DIO2 expression was inversely related to the anti-inflammatory genes ADIPOQ and PPARgamma in both VAT and SAT, but of the proinflammatory genes, only PAI-1 had a significant relationship to DIO2 expression.
Pode ser denominada de Acrp-30 (30-K Da adipocyte complementrelated protein), apM1 e adipoQ, considerando que fora, simultaneamente, identificada por diferentes grupos (Kershaw e colaboradores, 2004; Fosenca-Alaniz e colaboradores, 2006; Ahima, 2006; Kadowaki e colaboradores, 2006; Pinto, 2014).
Peralta-Romero JDJ, Karam-Araujo R, Burguete-Garcia AI, Estrada-Velasco BI, Lopez-Islas C, Figueroa-Arredondo PMDC, Valladares-Salgado A, Cruz M (2015) ADIPOQ and ADIPOR2 gene polymorphisms: association with overweight/obesity in Mexican children.
Spiegelman, "AdipoQ is a novel adipose-specific gene dysregulated in obesity," The Journal of Biological Chemistry, vol.
In addition, recent study reported that progestin and adipoQ receptors 3 (PAQR3), as a novel anchoring protein of SCAP/SREBP complex, also can regulate cholesterol biosynthesis and SREBP activation [7].
Using HExpoCHem, PCB 126 was associated, though not statistically significantly, with insulin sensitivity via a protein complex of ADIPOQ (p > 0.05), and with arterial hypertension via a protein complex of AGTR1 and another complex of NOS3 (both p > 0.05).
In another study, the same team of researchers found that centenarians and their offspring also had present a genetic variant of the ADIPOQ gene, which expresses higher amounts of the hormone adiponectin.