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Related to ADPase: apyrase, PGI2


 (ăp′ə-rās′, -rāz′)
Any of various enzymes that catalyze the hydrolysis of ATP or ADP, producing AMP and inorganic phosphate and releasing energy.

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


any of various enzymes that catalyse the hydrolysis of adenosine triphosphate, yielding a phosphate and energy
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
References in periodicals archive ?
Platelets are stabilized in vivo by such mediators as nitric oxide, prostaglandin I2, prostacyclin, and endothelial ADPase to prevent pathologic thrombus formation.
Platelets are continually exposed to a number of activating factors, such as collagen, thrombin, ADP, fibrinogen, vWF, and inhibitory factors such as prostacyclin ([PGI.sub.2]) and ADPase [33].
In the absence of 10% DMSO, the adults worms homogenized presented an ADPase activity of 76.49 [+ or -] 11.47 nmol Pi [mg.sup.-1] [min.sup.-1] and an ATPase activity of 55.80 [+ or -] 8.36 nmol Pi [mg.sup.-1] [min.sup.-1].
In the present work, we aimed to determine whether ecto-nucleotidases activities (ATPase, ADPase, and AMPase) are present and measurable in the ultrasound-guided aspirated contents of ovarian cysts and whether these activities are altered in endometriotic cysts compared with simple cysts, affecting the inflammatory condition of endometriosis.
The reaction medium used to assay ADPase activity contained 120 mM NaCl, 5.0 mM KCl, 60 mM glucose, 5 mM Ca[Cl.sub.2], and 50 mM Tris-HCl buffer, pH 7.5 in a final volume of 200 [micro]L.
Briefly, the single cell suspensions (5-10 x [10.sup.4] cells) were incubated for 45-60 min at 37[degrees]C in a final volume of 80 [micro]L RPMI-1640 in neutral pH supplemented with 4 mmol/L [beta]-glycerophosphate and the following tracer substrates: 500 [micro]M [[sup.3]H]ATP (ATPase), 500 [micro]M [[sup.3]H]ADP (ADPase), 300 [micro]M [[sup.3]H]AMP (ecto-57-nucleotidase), 300 [micro]M [[sup.3]H]adenosine (adenosine deaminase), and 400 [micro]M [[sup.3]H]AMP plus 600 [micro]M [gamma]-phosphate-donating ATP (adenylate kinase).