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A substance, C7H17NO3, that is derived from choline and is released at the ends of nerve fibers in the somatic and parasympathetic nervous systems, where it mediates the transmission of nerve impulses.


(ˌæsɪtaɪlˈkəʊliːn; -lɪn)
(Biochemistry) a chemical substance secreted at the ends of many nerve fibres, esp in the autonomic nervous system, and responsible for the transmission of nervous impulses. Formula: CH3CO2(CH2)2N(CH3)3+


(əˌsit lˈkoʊ lin, əˌsɛt-)

a short-acting neurotransmitter, widely distributed in the body, that functions as a nervous system stimulant, a vasodilator, and a cardiac depressant.
Abbr.: ACh
a•ce`tyl•cho•lin′ic (-ˈlɪn ɪk) adj.


A neurotransmitter that triggers activity by muscles or secretory glands.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.acetylcholine - a neurotransmitter that is a derivative of cholineacetylcholine - a neurotransmitter that is a derivative of choline; released at the ends of nerve fibers in the somatic and parasympathetic nervous systems
neurotransmitter - a neurochemical that transmits nerve impulses across a synapse
References in periodicals archive ?
During pregnancy, nicotine in tobacco smoke stimulates acetylcholine receptors, and causes structural changes in the brain.
Cytisine is a plant-based alkaloid that, like varenicline, is a partial agonist of nicotinic acetylcholine receptors.
So, to conduct this work, Yale University School of Medicine researchers used single photon emission computed tomography to quantify the availability of nicotinic acetylcholine receptors (B2-nAChRs) in smoking and nonsmoking individuals with schizophrenia and healthy subjects.
Inclusion of alpha-bungarotoxin, a nicotinic acetylcholine receptor antagonist, or cycloheximide, a protein synthesis inhibitor, during nicotine treatment abolished nicotine-induced podosome rosette formation in the rat cells, suggesting that signalling through the nicotinic acetylcholine receptors and synthesis of new proteins are required for podosome rosette formation.
Investigations have shown that it is a complete agonist of [alpha]7 nicotinic acetylcholine receptors (4).
Nicotinic acetylcholine receptors (nAChR) play major roles in the fast synapse cholinergic transmission in insect central nervous system (Gundelfinger & Schulz 2000).
An important role of parasympathetic cholinergic neurons and postsynaptic muscarinic acetylcholine receptors in the contraction of gastric smooth muscle has been provided in functional studies (Makhlouf and Murthy, 2006).
This potential new drug target belongs to a class of receptors called the nicotinic acetylcholine receptors (nAChRs).
Systemic inflammation leads to resistance to atracurium without increasing membrane expression of acetylcholine receptors.
Nicotinic acetylcholine receptors have many functions, and in the brain are the primary targets of nicotine.
Dr Taslim discovered that the simultaneous administration of nicotine and ethanol to mice resulted in marked improvement of impairment of motor coordination mediated by nicotinic acetylcholine receptors and subtype agonists.
Clinical correlations of antibodies that bind, block, or modulate human acetylcholine receptors in myasthenia gravis.

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