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A substance, C7H17NO3, that is derived from choline and is released at the ends of nerve fibers in the somatic and parasympathetic nervous systems, where it mediates the transmission of nerve impulses.


(ˌæsɪtaɪlˈkəʊliːn; -lɪn)
(Biochemistry) a chemical substance secreted at the ends of many nerve fibres, esp in the autonomic nervous system, and responsible for the transmission of nervous impulses. Formula: CH3CO2(CH2)2N(CH3)3+


(əˌsit lˈkoʊ lin, əˌsɛt-)

a short-acting neurotransmitter, widely distributed in the body, that functions as a nervous system stimulant, a vasodilator, and a cardiac depressant.
Abbr.: ACh
a•ce`tyl•cho•lin′ic (-ˈlɪn ɪk) adj.


A neurotransmitter that triggers activity by muscles or secretory glands.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.acetylcholine - a neurotransmitter that is a derivative of cholineacetylcholine - a neurotransmitter that is a derivative of choline; released at the ends of nerve fibers in the somatic and parasympathetic nervous systems
neurotransmitter - a neurochemical that transmits nerve impulses across a synapse
References in periodicals archive ?
They also demonstrated blocking acetylcholine receptors disrupts learning and memory.
However, the fact that atropine, an antagonist of muscarinic acetylcholine receptors (18), did not modify the direct vasorelaxation produced by clobenzorex on rat aortic segments excludes the possible involvement of stimulation of muscarinic acetylcholine receptors in the vasodilator responses produced by this appetite suppressant drug.
The possible mechanism employed by Alfa Interferon therapy in causing myasthenia gravis is by production of autoantibodies against the acetylcholine receptors through its immunomodulatory action are the antibodies produced against nuclear and thyroid antigens and insulin.
The antidote atropine combats the symptoms by blocking the victims' acetylcholine receptors.
During pregnancy, nicotine in tobacco smoke stimulates acetylcholine receptors, and causes structural changes in the brain.
Cytisine is a plant-based alkaloid that, like varenicline, is a partial agonist of nicotinic acetylcholine receptors.
Effects of blockade of a4p2 and a7 nicotinic acetylcholine receptors on cue-induced reinstatement of nicotine-seeking behaviour in rats.
Neonicotinoids are classes of insecticides known to selectively target insect nicotinic acetylcholine receptors.
Isoclast, developed by Dow AgroSciences, exhibits interactions with nicotinic acetylcholine receptors (nAChR) in the insects that are distinct from those observed with alternative neonicotinoid insecticides.
So, to conduct this work, Yale University School of Medicine researchers used single photon emission computed tomography to quantify the availability of nicotinic acetylcholine receptors (B2-nAChRs) in smoking and nonsmoking individuals with schizophrenia and healthy subjects.
15) Research work done by Foulds also explains the basis of partial agonist of [alpha]4[beta]2 nicotinic acetylcholine receptors in the treatment of nicotine dependence.

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