Tirbanibulin ointment has been well tolerated in patients with psoriasis and also in trials treating patients with actinic keratosis.
Positive topline efficacy and safety results from two Phase III studies of tirbanibulin ointment 1% in the treatment of actinic keratosis were presented at the American Academy of Dermatology in a late breaker oral presentation.
The company is researching creams for nail fungus, dry and scaly skin, anal fissures and actinic keratosis.
The clinical studies results have been consistent between Phase II and the two Phase III studies, highlighting the consistency of this treatment in patients with actinic keratosis.
We believe KX2-391 has the potential to change the paradigm of topical therapy for Actinic Keratosis.
KX2-391, also known as KX-01, is a first-in-class dual Src kinase and tubulin polymerization inhibitor in Phase III development as a topical medicinal product for the treatment of actinic keratosis.
Actinic keratosis is a common skin condition that is induced through ultra-violet light damage, resulting in patches of thick, scaly, or crusty skin.
For new basal cell cancers, the rate was 20% lower in the treatment group, 30% lower for the squamous cell cancers, and 13% lower for actinic keratosis.
As it turns out, there was a lower rate of sunscreen use over the 12 months in the nicotinamide group.
Warnings 6-10 describe more specific forms of Viral Infection: (6) Non-Hyperkeratotic Actinic Keratosis, (7) Actinic Keratosis of Face and Anterior Scalp, (8) Non-Hyperkeratotic Non-Pigmented Actinic Keratosis, (9) Non-Hyperkeratotic Face and Scalp Actinic Keratosis, (10) Pigmented Actinic Keratosis.
From your detailed description, however, it sounds like you could have Actinic Keratosis.
You should seek a doctor or even a dermatology opinion, particularly because of the bleeding.
In the study by Carag et al (6) step sections (10 slides at 50-[micro]m intervals) revealed new diagnostic findings in 33% of biopsies with an initial diagnosis of actinic keratosis.
In our study, step sections (3 slides at 50-[micro]m intervals) resulted in new findings in 7% of small skin biopsies or curettings.
A pharmacokinetic evaluation of 0.5% and 5% fluorouracil topical cream in patients with actinic keratosis.
Certainly excision is an option for the treatment of a solitary actinic keratosis.
However, most patients have multiple actinic keratoses, and a surgical excision is not practical or necessary.