Bisphosphonates, which include alendronate (Fosamax), risedronate (Actonel
), zoledronic acid (Reclast), and ibandronate (Boniva) are recommended as the initial treatment.
On the other hand, if an osteoporotic patient simply can't tolerate guideline-recommended initial therapy with an oral bisphosphonate such as alendronate (Fosamax)or risendronate (Actonel
), there's no need to bring in a specialist.
Some of the brands in Theramex's portfolio include Ovaleap, Zoely, Estreva, Seasonique, Actonel
Importantly, for the non-generic business, Actavis will continue to promote and distribute branded medicines in the portfolio including but not limited to products such as Actonel
Patent expirations in 2014 included Nexium, Celebrex and Actonel
, collectively representing sales of some $7.5 billion.
Oral bisphosphonates--alen-dronate (Fosamax), risedronate (Actonel
), and ibandronate (Boniva)--are often the first-line treatments for osteoporosis.
]hey are raloxifene (Evista), bisphosphonates (Actonel
, Boniva, Fosamax, Reclast), parathyroid hormone, denosumab (Prolia), and calcitonin (Fortical, Miacalcin) (Level A evidence).
The guidelines also advocate medical therapy with zoledronic acid or other bisphosphonate drugs--alendronate (Fosamax), risedronate (Actonel
), or deno-sumab (Prolia)--or teriparatide (Forteo) for men with a history of hip or spinal fracture and men at high risk of fracture based on DXA results and clinical risk factors.
Most of them are looking for solutions other than bisphosphonates like Fosamax, Actonel
, and Boniva.
But bisphosphonates -- such as Merck's Fosamax, Roche's Boniva, Novartis's Reclast, and Warner Chilcott's Actonel
-- remain the most popular option, and can be bought for as little as $10 per month in the US.
L'etude FACT, pour Fosamax Actonel
Comparison Trial, a montre que ces 2 traitements ralentissent la destruction de l'os, et favorisent la reconstruction d'os neuf.
The lead compounds are chemically modified forms of the osteoporosis drugs Actonel
(Risedronate) and Zometa (Zoledronate), Oldfield said.