The genes for some adhesins
(esp and agg/asa1) were more prevalent in non-invasive Enterococcus spp.
Covering in turn virulence mechanisms and important bacterial diseases in agriculture, they discuss such aspects as fimbrial and afimbrial adhesins
involved in bacterial attachment to surfaces, high-throughput DNA sequencing technology as a tool in understanding plant-pathogen bacteria, Candidatus liberibacter species and related diseases, virulence mechanisms of plant-pathogen Ralstonia species, and mechanisms of pathogenicity and the emergence of new plant-pathogen species in the genus Streptomyces.
Availability of key nutrients, chemotaxis towards surface, surface adhesins
and presence of surfactants are some factors which influence biofilm formation.
antimicrobial agents); (3) adhesins
used to attach or adhere to specific surfaces or tissues; (3) enzymes to mediate specific reactions on the cell surface important in the survival of the organism; (4) protective structures against phagocytic engulfment or killing; (5) antigenic disguises to bypass activation of host immune defenses; (6) endotoxins, generally cell wall components, that cause an inflammatory response in the host; (7) "sensing proteins" that can respond to temperature, osmolarity, salinity, light, oxygen, nutrients, etc.
coli produced adhesins
(K99 or F41), but expressed F17 adhesive factor.
influenzae revealed a plethora of novel adhesins
that might play a critical role in host--pathogen interactions.
The researcher says that these findings suggest that disruption or modulation of this interaction of bacterial adhesins
with the receptor might offer unexpectedly broad protection against bacterial meningitis, and may provide a therapeutic target for the prevention and treatment of disease.
The cell surface sugar residues, as defined by these lectin probes, may bind to the aggregation factor (MAF) or to endogenous lectins; they may also function as adhesins
towards bacteria, algae, etc.
The other approach we're excited about is to develop therapeutic compounds that block the assembly of these adhesins
," he adds.
In March 1999, Inhibitex signed an exclusive licensing and research agreement with BioResearch Ireland (BRI), to discover and characterise cell surface adhesins
from Staphylococcus aureus and coagulase-negative staphylococci.
are molecules or structures that are present extracellularly on the bacterial cell surface.
3) Pathogenicity of Escherichia coli is due to different gene-encoding virulence factors (VFs), such as adhesins
, toxins etc.