congenital adrenal hyperplasia

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congenital adrenal hyperplasia

n.
Any of a group of genetic disorders characterized by an enzyme deficiency that leads to insufficient production of cortisol and often aldosterone by the adrenal glands, typically resulting in abnormally high androgen secretion, masculinization of the female genitourinary system, high blood pressure, and, in the most severe cases, uncontrolled blood sodium depletion.
References in periodicals archive ?
Control of childhood congenital adrenal hyperplasia and sleep activity and quality with morning or evening glucocorticoid therapy.
GlobalData's clinical trial report, "Congenital Adrenal Hyperplasia (Adrenogenital Syndrome) Global Clinical Trials Review, H2, 2015" provides an overview of Congenital Adrenal Hyperplasia (Adrenogenital Syndrome) clinical trials scenario.
The two main subtypes of primary aldosteronism are idiopathic hyperaldosteronism (IHA), also known as bilateral adrenal hyperplasia, which accounts for two-thirds of all cases, and unilateral aldosterone-producing adenoma, which accounts for the remaining third.
To the Editor: Nonclassic congenital adrenal hyperplasia (NCAH) due to 21-hydroxylase deficiency (21-OHD) is one of the most common autosomal recessive disorders.
(11) Bilateral adrenal hyperplasia (idiopathic hyperaldosteronism) accounts for 65% of sporadic cases of primary aldosteronism.
In the last six months, through this screening, Latifa Hospital detected and treated seven cases of congenital hypothyroidism and three cases of congenital adrenal hyperplasia.
Little Oranye Chimweokwu Sayne was brought to Max Super Speciality Hospital, Shalimar Bagh recently where she was diagnosed with a rare genetic disorder called Congenital Adrenal Hyperplasia whereby the body does not produce the vital 21- hydroxylase enzyme leading to enlargement of the clitoris.
It has been backed with equity finance from Finance Wales - which maintains a minority interests in the business Its lead product Chronocort was recently the subject of a positive phase two trial in the treatment of congenital adrenal hyperplasia. It is now due to enter pivotal phase three studies in the first half of 2015.
"I hope you will also take the time to read some of the many comments I have received from constituents, including the story of a two-year-old with Congenital Adrenal Hyperplasia who owes his life to the Huddersfield A&E Department and those of many other constituents whose lives were saved by being able to reach essential services in time.
Obesity, medical conditions like Albright syndrome, congenital adrenal hyperplasia or hypothyroidism, or coming into direct contact with hormones oestrogen or testosterone are some of them.
Prof Philippe Bouchard, the ESE president and author of numerous published works on endocrinology, confirmed that the comprehensive programme was structured over 20 sessions, a combination of lectures and interactive workshops, including the latest on hyperparathyroidism, congenital adrenal hyperplasia and minimally invasive adrenal surgery.
Ten of the 31 chapters describe the symptoms, cause, diagnosis, and treatment of the many disorders resulting from congenital adrenal hyperplasia. Other contributions discuss marsupial pathway, androgen insensitivity syndrome, the persistant Mullerian duct syndrome, apparent mineralocorticoid excess, animal models of adrenal genetic disorders, geographical endocrinology, and prenatal diagnosis.
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