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A statin drug, C24H36O5, that blocks the body's synthesis of cholesterol and is used to lower cholesterol (especially LDL) levels and to reduce the risk of heart attack and stroke in individuals with elevated risk.

[lo-, of unknown origin + -vastatin, statin suffix; see pravastatin.]


(Pharmacology) a drug, of the statin class, used to reduce cholesterol. Formula: C24H36O5


(ˌloʊ vəˈstæt n)
a drug that reduces the levels of fats in the blood by altering the enzyme activity in the liver that produces lipids.
[1985–90; of undetermined orig.]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.lovastatin - an oral drug (trade name Mevacor) to reduce blood cholesterol levels; used when dietary changes have proved inadequate
lipid-lowering medication, lipid-lowering medicine, statin, statin drug - a medicine that lowers blood cholesterol levels by inhibiting HMG-CoA reductase


n lovastatina
References in periodicals archive ?
where he oversaw the growth of Niaspan (niacin extended-release) and the launch of Advicor (niacin extended-release/lovastatin).
In the ADvicor Versus Other Cholesterol-modulating Agents Trial Evaluation (ADVOCATE), the combination of niacin ER plus lovastatin was more effective than either atorvastatin or simvastatin alone in increasing LDL peak particle diameter and was more effective than either atorvastatin or simvastatin alone in increasing the proportion of HDL in "cardio protective" 2b subclass.
Reddy's Aceon Solvay Cobalt Pharma Actonel P&G Teva Actoplus Met Eli Lilly/Takeda Mylan Advicor Abbott FDA web-sub 5/22/08 Advicor Abbott FDA web-sub 9/22/08 Advicor Abbott FDA web-sub 12/17/08 Aldara cream 3M FDA web-sub 10/17/06 Alimta Eli Lilly Teva Alimta Eli Lilly Teva Allegra D-24 Aventis Dr.
xx Advicor, Altocor, Altoprev, Caduet, cholestyramine, cholestyramine light, Colestid, Crestor, fenofibrate, gemfibrozil, Lescol, Lescol XL, Lipitor, Locholest, Lofibra, Lopid, lovastatin, Mevacor, Niaspan, Pravachol, Pravigard PAC, Prevalite, Questran, Questran Light, Tricor, Welchol, Zetia, Zocor Depression 296.
TABLE: SIMILAR SOUNDING DRUG NAMES THAT COULD RESULT IN A MEDICATION ERROR Drug Name Confused With Abelcet Amphotericin B Accupril Aciphex Acetazolamide Acetohexamide Aciphex Aricept Aciphex Accupril Activase TNKase Actonel Actos Adderall Inderal Advicor Altocor Aggrastat Argatroban Adapted from Medication Safety Alert.
The three-year agreement on the drugs, Niaspan and Advicor, will take effect in January, enabling Takeda Pharmaceuticals North America Inc.