We use them as models to study whether intracellular signaling in vivo is governed extrinsically, by noradrenergic afferent fibers
releasing neuromodulators in defined spatiotemporal patterns and therefore by receptor-specific activation dynamics or rather intrinsically, by compartmentalization of cellular components, resulting in spatiotemporally different signaling outputs.
This finding suggests that neurotoxin-sensitive afferent fibers
carry the peripheral stimulus involved in GE delay.
Abundant TRPA1 expression was detected in vagal afferent fibers
Cardiovascular reflex control by afferent fibers
from skeletal muscle receptors, In: Shepherd JT et al.
Indeed, electrophysiologic recordings performed in subsequent years showed that inputs carried by the afferent fibers
of the trigeminal nerve ophthalmic branch in the paralytic side cause increased excitability of the blink reflex in the non-paralytic side and proved quantitatively that the same increase cannot be provided by the inputs carried by the afferent fibers
in the non-paralytic side (5).
Basically, these are annulospiral stretch receptors with Ia afferent fibers
, synapse in the SC and an efferent axon of lower a motor neuron that causes muscle contraction.
The number of runs was approximately the number of afferent fibers
contemporary stimulated by a single electrode of the cochlear prosthesis; this number was calculated by considering the size of the electrode (0.3 mm), the diameter of a IHC ([approximately equal to]10 gm), and the number of auditory fibers ([approximately equal to]10) contacting a single IHC.
Indeed, peripheral somatosensory stimulation evoked near the motor threshold activates proprioceptive, sensory and cutaneous afferent fibers
Interestingly, AF occurs with the stimulation at the wrist level (mixed-nerve stimulation) of the median nerve but is not seen with the stimulation of skin branches (digital nerve) from the second finger This may suggest that this facilitation occurs through thick afferent fibers
stemming from muscle spindles (51,53).
Excitation of lateral vestibular neurons by peripheral afferent fibers
. J Neurophysiol 1966; 29: 508.
In addition, there are individual variations of pelvic anatomy and neurophysiology, intermingling of afferent fibers
, intercommunication among nerve plexuses, and cross-talk (19).
Under physiological conditions, potentially harmful stimuli are integrated by the nociceptors of primary afferent fibers
and relayed for final processing in the supraspinal centers.