The cytokine IL-4 is involved in allergic inflammation
and airway remodeling (33).
Although protein expression for IL-22 BP remains to prove, our preliminary study suggests that IL-22 BP may play a role in a Th2 cytokine driven allergic inflammation
as natural antagonist for IL-22.
In light of recent developments surrounding tumor immunotherapy, the researchers decided to combine 5-FU with calcipotriol (calcipotriene, approved for psoriasis), which induces thymic stromal lymphopoietin (TSLP), "an epithelium-derived cytokine and a master regulator of allergic inflammation
in the skin," according to the authors.
10,11 Eotaxin is an eosinophil-specfic CC chemokine associated with the recruitment of eosinophils to the site of allergic inflammation
Which allergic inflammation
of the nose is also the title of a comedy by Noel Coward?
In this proposal, we will address the role of extracellular miRNAs for the normal T cell development and during allergic inflammation
of the airways.
In murine models of allergic inflammation
, IFN-[gamma] has been shown to prevent the development of antigen-induced airway eosinophilia and hyper-responsiveness.
Recently, many clinical and experimental studies about the cells and the mediators involved in initiating and perpetuating ocular allergic inflammation
have broadened our knowledge about the pathophysiology of this disease.
Animal studies have shown that a maternal diet rich in methyl donors can enhance susceptibility to allergic inflammation
in the offspring, mediated through increased DNA methylation.
Interestingly, the animals showed considerable reduction in the allergic inflammation
response to dust mite extract and created immune cells that were less capable of prompting inflammatory responses in airways.
caused by inappropriate immune responses to some types of food has become a major public health issue.
This increased gene expression matters because it can cause white blood cells called mononuclear cells to produce far greater amounts of inflammatory factors like interleukin 4, LIGHT and lymphotoxin beta receptor which contribute to allergic inflammation
and other abnormalities in the bronchial passages in asthma.