alpha

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Related to Alpha cells: insulin, Beta cells, Delta cells

al·pha

 (ăl′fə)
n.
1. The first letter of the Greek alphabet. See Table at alphabet.
2. The first of a series; the beginning.
3. Astronomy The brightest star in a constellation.
4.
a. The mathematical estimate of the return on a security when the return on the market as a whole is zero. Alpha is derived from a in the formula Ri = a + bRm, which measures the return on a security (Ri) for a given return on the market (Rm) where b is beta.
b. The return on an investment portfolio that can be attributed to the skill of the portfolio's manager rather than the performance of the market.
adj.
1. Being the highest ranked or most dominant individual of one's sex. Used of social animals: the alpha female of the wolf pack.
2. Chemistry
a. Being in the first position relative to a designated carbon atom in an organic molecule at which an atom or a group may be substituted.
b. Referring to the first of a group of isomers, or molecules of similar origin or properties, determined arbitrarily by those who discover or classify them. Used in combination: alpha-tocopherol.
3. Alphabetical.

[Greek, of Phoenician origin; see ʔlp in Semitic roots.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

alpha

(ˈælfə)
n
1. (Letters of the Alphabet (Foreign)) the first letter in the Greek alphabet (Α, α), a vowel transliterated as a
2. (Education) Brit the highest grade or mark, as in an examination
3. (General Physics) (modifier)
a. involving or relating to helium-4 nuclei: an alpha particle.
b. relating to one of two or more allotropes or crystal structures of a solid: alpha iron.
c. relating to one of two or more isomeric forms of a chemical compound, esp one in which a group is attached to the carbon atom to which the principal group is attached
4. (modifier) denoting the dominant person or animal in a group: the alpha male.
[via Latin from Greek, of Phoenician origin; related to Hebrew āleph, literally: ox]

Alpha

(ˈælfə)
n
1. (Astronomy) (foll by the genitive case of a specified constellation) usually the brightest star in a constellation: Alpha Centauri.
2. (Communications & Information) communications a code word for the letter a
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

al•pha

(ˈæl fə)

n., pl. -phas,
adj. n.
1. the first letter of the Greek alphabet (Α, α).
2. the first; beginning.
3. (cap.) the brightest star in a constellation: Alpha Centauri.
4. the first or foremost in a series of related items.
adj.
5.
a. (esp. of animals) having the highest rank of its sex in a dominance hierarchy: the alpha female.
b. being the most prominent, talented, or aggressive person in a group: the alpha male of investment bankers.
6. pertaining or linked to the carbon atom closest to a particular group in an organic molecule.
[< Latin < Greek álpha < Semitic; compare aleph]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.alpha - the 1st letter of the Greek alphabetalpha - the 1st letter of the Greek alphabet
Greek alphabet - the alphabet used by ancient Greeks
alphabetic character, letter of the alphabet, letter - the conventional characters of the alphabet used to represent speech; "his grandmother taught him his letters"
2.alpha - the beginning of a series or sequencealpha - the beginning of a series or sequence; "the Alpha and Omega, the first and the last, the beginning and the end"--Revelations
start - the beginning of anything; "it was off to a good start"
Adj.1.alpha - first in order of importancealpha - first in order of importance; "the alpha male in the group of chimpanzees"; "the alpha star in a constellation is the brightest or main star"
important, of import - of great significance or value; "important people"; "the important questions of the day"
2.alpha - early testing stage of a software or hardware productalpha - early testing stage of a software or hardware product; "alpha version"
explorative, exploratory - serving in or intended for exploration or discovery; "an exploratory operation"; "exploratory reconnaissance"; "digging an exploratory well in the Gulf of Mexico"; "exploratory talks between diplomats"
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.

alpha

noun
the alpha and omega first and last, be-all and end-all He was the alpha and omega of the comedy series.
Collins Thesaurus of the English Language – Complete and Unabridged 2nd Edition. 2002 © HarperCollins Publishers 1995, 2002
Translations
alfa
alfa
alfa
alfa
알파
alpha
alfa
alfa

alpha

[ˈælfə]
A. N (= letter) → alfa f (Brit) (Scol, Univ) → sobresaliente m
B. CPD alpha particle N (Phys) → partícula f alfa
alpha rhythm, alpha wave N (Physiol) → ritmo m alfa
Collins Spanish Dictionary - Complete and Unabridged 8th Edition 2005 © William Collins Sons & Co. Ltd. 1971, 1988 © HarperCollins Publishers 1992, 1993, 1996, 1997, 2000, 2003, 2005

alpha

n
(= letter)Alpha nt
(Brit Sch, Univ) → Eins f; alpha plusEins (→ plus (hum)); (Sch also) → Eins (→ mit Stern (hum))

alpha

:
alpha particle
nAlphateilchen nt
alpha ray
nAlphastrahl m
alpha rhythm, alpha wave
n (Physiol) → Alpharhythmus m
Collins German Dictionary – Complete and Unabridged 7th Edition 2005. © William Collins Sons & Co. Ltd. 1980 © HarperCollins Publishers 1991, 1997, 1999, 2004, 2005, 2007

alpha

[ˈælfə]
1. nalfa m or f inv
2. adj (Phys) alpha particleparticella f alfa inv
Collins Italian Dictionary 1st Edition © HarperCollins Publishers 1995

alpha

n alfa; — fetoprotein alfa fetoproteína; — galactosidase alfa galactosidasa; — hydroxy acids ácidos alfa hidróxidos; — methyldopa alfa metildopa
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
References in periodicals archive ?
It is characterized by excessive production of glucagon by the alpha cells of the Langerhans islands and locates mainly in the pancreatic tail due to the accumulation of islands in this part of the organ.
As expected, some of the cells had similar gene-expression patterns to cells that produce hormones in the human pancreas: glucagon-producing alpha cells and insulin-producing beta cells.
Pancreatic endocrine cells include all hormone-producing cells, such as insulin-producing beta cells and glucagon-producing alpha cells, within the islet of Langerhans, whereas the duct cells are epithelial cells that line the ducts of the pancreas.
In a 68-year-old alcoholic, the number of beta cells decreased, and the alpha cells increased (Fig.
The prevailing theory is that this decrease in the I:G ratio is caused by beta-cell apoptosis and transdifferentiation to alpha cells. T2DM patients also have increased amyloid deposits, the result of increased islet amyloid polypeptide.
Glucagon is synthesised in the alpha cells of the pancreas in response to low PGC.
This in turn causes enhanced glucagon production by alpha cells in the pancreas.
In early 2017, in a paper published in the journal Cell, a European team reported that the antimalarial drug artemether could convert alpha cells into functional beta cells.
In a recently published study in Nature, it is demonstrated that SGLT2 is expressed in glucagon- secreting alpha cells of the pancreatic islets.14 The investigators further found that expression of SLC5A2 (which encodes SGLT2) was lower and glucagon (GCG) gene expression was higher in islets from type 2 diabetic individuals and in normal islets exposed to chronic hyperglycemia than in islets from non-diabetics.
glucagon-like peptide-1 secretion from L cells and alpha cells. Nat Med.
GLP-1 is a naturally-occurring peptide hormone that is released within minutes after eating a meal and is known to suppress glucagon secretion from pancreatic alpha cells and stimulate glucose-dependent insulin secretion by pancreatic beta cells.