Chiba, Molecular mechanism in alpha-glucosidase
and glucoamylase, Biosci.
Anti-inflammatory, free radical scavenging and alpha-glucosidase
inhibitory activities of Hamelia patens and its chemical constituents.
These data will be highlighted in a poster entitled "Development of a Novel Gene Therapy for Pompe Disease: Engineered Acid Alpha-Glucosidase
Transgene for Improved Expression and Muscle Targeting," at the American Society of Gene & Cell Therapy, or ASGCT, 22nd Annual Meeting in Washington, D.C.
Biologics technology company WuXi Biologics (Stock code:2269.HK) reported on Wednesday the receipt of the US FDA's breakthrough therapy designation for AT-GAA (ATB200/AT2221) in late onset Pompe disease, an inherited lysosomal storage disorder caused by the deficiency of an enzyme known as acid alpha-glucosidase
PIONEER 10 was a 57-week, randomised, open-label, active-controlled, parallel-group, multi-centre, single country trial with four treatment arms, comparing the safety, tolerability and efficacy of 3, 7 and 14 mg oral semaglutide with 0.75 mg dulaglutide (the approved dose by the Pharmaceutical and Medical Devices Agency (PMDA) in Japan) in Japanese people with type 2 diabetes inadequately controlled with one oral antidiabetic drug (sulfonylurea, glinide, thiazolidinedione, alpha-glucosidase
inhibitor or sodium glucose cotransporter-2 inhibitor).
inhibitors (including acarbose and miglitol) delay breakdown of carbohydrates in the small intestine, and lower postprandial glucose and insulin levels.
Completing the Philippine delegation were: Leann Patrice Ganzon and Anne Nicole Occena of INHS who submitted their study on Garcinia binucao Fruit and Leaf: Phytochemicals-Mediated Antioxidant, Alpha-Amylase and Alpha-Glucosidase
Enzyme Inhibitors; Adrian Maglasang of City of Bogo Science and Arts Academy in Cebu who conducted a research on the Propulsion Performance Evaluation of a Lego-Based Carangiform Mechanism for a Prototype Robotic Fish Unmanned Underwater Vehicle; and Roehann Mykael Zabat of Juan R.
Several intervention studies have demonstrated that onset of diabetes can be prevented or delayed with intensive lifestyle modification and oral antidiabetic agents including metformin, thiazolidinediones and alpha-glucosidase
Background: Pompe disease is a rare lysosomal glycogen storage disorder linked to the acid alpha-glucosidase
Soybean phenolic-rich extracts inhibit key-enzymes linked to type 2 diabetes (alpha-amylase and alpha-glucosidase
) and hypertension (angiotensin I converting enzyme) in vitro.
In vitro alpha-glucosidase
and alph[alpha]-amylase enzyme inhibitory effects of Andrographis paniculata extract and andrographolide.