melanocyte-stimulating hormone

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mel·a·no·cyte-stim·u·lat·ing hormone

 (mĕl′ə-nō-sīt′stĭm′yə-lā′tĭng, mə-lăn′ə-)
n. Abbr. MSH
A hormone secreted by the pituitary gland that regulates skin color in humans and other vertebrates by stimulating melanin synthesis in melanocytes and melanin granule dispersal in melanophores. Also called intermedin.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

MSH

melanocyte-stimulating hormone: a pituitary gland hormone that causes darkening of the skin by increasing the production of melanin.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.melanocyte-stimulating hormone - a hormone secreted by the anterior pituitary gland that controls the degree of pigmentation in melanocytes
endocrine, hormone, internal secretion - the secretion of an endocrine gland that is transmitted by the blood to the tissue on which it has a specific effect
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
References in periodicals archive ?
Alpha-MSH binds to the melanocortin-4-receptor (MC4R).
Solar elastosis has been shown to be secondary to the synthesis of alpha-melanocyte stimulating hormone (alpha-MSH) and adrenocorticotropic hormone (ACTH) derived from pro opiomelanocortin (POMC) in keratinocytes.
Lipton, "Alpha-MSH modulates local and circulating tumor necrosis factor-alpha in experimental brain inflammation," The Journal of Neuroscience, vol.
Bremelanotide, which is a melanocortin 4 receptor agonist drug candidate, is a synthetic peptide analog of the naturally occurring hormone alpha-MSH (melanocyte-stimulating hormone).
Age-related alterations in the central thermoregulatory responsiveness to alpha-MSH. J Therm Biol 2015;49-50:9-15.
Alpha-MSH when released from the anterior pituitary, is a potent natural antipyretic agent that antagonizes the fever induced by IL-1, IL-6 and TNF-alpha.
The involvement of p38 mitogen-activated protein kinase in the alpha-melanocyte stimulating hormone (alpha-MSH)-induced melanogenic and anti-proliferative effects in B16 murine melanoma cells.

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