The drug classes include angiotensin receptor blockers, such as Novartis AG's Diovan, calcium channel blockers, like Pfizer Incs's Norvasc, ACE inhibitors, including Pfizer's Altace
, and diuretics, such as Merck & Co Inc's Hyzaar.
The JNC 8 writers suggested doctors choose from an angiotensin-converting enzyme inhibitor (ACEI, such as Altace
, Vasotec, Lotensin), angiotensin receptor blocker (ARB, such as Benicar, Diovan), calcium channel blocker (CCB, such as Norvasc, Procardia) or thiazide diuretic (such as Esidrix or Zaroxolyn).
Some commonly prescribe drugs in this class include captopril (Capoten), enalapril (Vasotec), lisinopril (Prinivel, Zestril), benazepril (Lotensin), fosinopril (Monopril), moexipril (Univasc), perindopril (Aceon), ramipril (Altace
) and trandolapril (Mavik).
I casually mentioned the problem to my cardiologist and he immediately said, "You take Altace
, an ACE inhibitor, I'll bet that is the problem." My general practitioner agreed that it's a common problem.
TYPES AND FUNCTIONS OF BLOOD PRESSURE DRUGS TYPE GENERIC NAME FUNCTION (BRAND NAME) Diuretics Furosemide Help rid the body of (Lasix) excess sodium and water Chlorthalidone (Hygroton) Beta blockers Acebutolol Reduce the heart rate, (Sectral) the heart's workload and its output of blood Atenolol (Tenormin) Betaxolol (Kerlone) Angiotensin-converting Ramipril Help reduce the enzyme (ACE) inhibitors (Altace
) production of angiotensin, which causes blood vessels to narrow Benazepril hydrochloride (Lotensin) Angiotensin II receptor Irbesarten Help prevent the blockers (ARBs) (Avapro) receptors in blood vessels from binding with angiotensin Eprosartan mesylate (Teveten) Valsartan (Diovan)
Medications included Lipitor, Altace
, Rhoxal-bisoprolol, and Aspirin.
ACE inhibitors (such as Capoten, Vasotec, Prinivil, Zestril, Monopril, Altace
, Accupril, Aceon, Mavic and Univasc) are less effective when combined with yohimbine, as are beta-blockers (such as Tenormin, Kerlone, Corego, Trandate, Lopressor, Toprol XL, Corgard, Levatol and Inderal).
King has been focused on making new painkillers since its top-selling blood-pressure pill Altace
went generic in 2007.
AGE inhibitors include Capoten, Prinivil, and Altace
. Beta blockers include Lopressor and Levatol.
* Alliance revenues include revenues from Amgen's sales of Enbrel, King Pharma's sales of Altace
, and J&J's sales of the Cypher drug-eluting stent, for which Wyeth makes the API of the eluted drug.