tRNA

(redirected from Aminoacyl-tRNA)
Also found in: Thesaurus, Medical, Wikipedia.

tRNA

abbr.
transfer RNA

transfer RNA



n.
any of a class of small, cloverleaf forms of RNA that transfer unattached amino acids in the cell cytoplasm to the ribosomes for protein synthesis.
Abbr.: tRNA
[1960–65]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.tRNA - RNA molecules present in the cell (in at least 20 varieties, each variety capable of combining with a specific amino acid) that attach the correct amino acid to the protein chain that is being synthesized at the ribosome of the cell (according to directions coded in the mRNA)tRNA - RNA molecules present in the cell (in at least 20 varieties, each variety capable of combining with a specific amino acid) that attach the correct amino acid to the protein chain that is being synthesized at the ribosome of the cell (according to directions coded in the mRNA)
ribonucleic acid, RNA - (biochemistry) a long linear polymer of nucleotides found in the nucleus but mainly in the cytoplasm of a cell where it is associated with microsomes; it transmits genetic information from DNA to the cytoplasm and controls certain chemical processes in the cell; "ribonucleic acid is the genetic material of some viruses"
References in periodicals archive ?
Called aminoacyl-tRNA synthetases (aaRSs), they link amino acids to RNA strings, playing an important role in the essential life process of converting genes into proteins.
Dirheimer, Comparative study of the effect of ochratoxin A analogues on yeast aminoacyl-tRNA synthases and on the growth and protein synthesis of hepatoma cells.
In the first step create a scalable and modular route to multiple new aminoacyl-tRNA synthetase/tRNA pairs that are orthogonal to each other and to endogenous synthetases and tRNAs.
Masayoshi Yamaguchi, Hidetoshi Oishi and Yasunobu Suketa, Zinc stimulation of bone protein synthesis in tissue culture: Activation of aminoacyl-tRNA synthetase, Biochemical Pharmacology, 37 (21), 4075-4080 (1988).
Phosphorylation of aminoacyl-tRNA synthetases could play a role in the regulation of protein synthesis in a similar manner as insulin regulates muscle (Kimball et al.
Interstitial lung disease with autoantibodies against aminoacyl-tRNA synthetases in the absence of clinically apparent myositis.
The correct amino acid is attached to each tRNA species by specific enzymes called aminoacyl-tRNA synthetases.
Aminoacyl-tRNA It catalyzes the esterification of a specific synthetase (AARS) amino acid or its precursor to one of all its compatible cognate tRNAs to form an aminoacyl- tRNA.
9:30 INVESTIGATING TRNA CHANNELING BY AMINOACYL-TRNA SYNTHETASES AND ELONGATION FACTOR TU
Tetracyclines bind reversibly to the 30S ribosomal subunit blocking the binding of aminoacyl-tRNA to the mRNA ribosome complex.
Even so, its genome is missing functions considered critical, such as aminoacyl-tRNA synthesis and translational release factors.
Separately, a 3-chlorotyrosinecharged tRNA containing a CUs anticodon, was prepared by a combination of chemical synthesis and enzymatic ligation, followed by aminoacylation of 3-chlorotyrosine using an aminoacyl-tRNA synthetase (Fig.