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A tricyclic antidepressant drug, C20H23N, used in the form of its hydrochloride salt.

[Perhaps ami(no)- + alteration of trypt(ophan) + -yl + -ine.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(ˌæmɪˈtrɪptɪˌliːn; -lɪn)
(Pharmacology) a tricyclic antidepressant drug. Formula: C20H23N
[C20: from amino + tryptamine + methyl + -ine2]
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


(ˌæm ɪˈtrɪp təˌlin, -ˌlaɪn, -lɪn)

a white crystalline powder, C20H23N, used to treat depression and enuresis.
[1960–65; ami(no)- + tri- + (he)ptyl (see heptane, -yl) + -ine1]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.amitriptyline - a tricyclic antidepressant drug (trade name Elavil) with serious side effectsamitriptyline - a tricyclic antidepressant drug (trade name Elavil) with serious side effects; interacts with many other medications
tricyclic, tricyclic antidepressant, tricyclic antidepressant drug - an antidepressant drug that acts by blocking the reuptake of norepinephrine and serotonin and thus making more of those substances available to act on receptors in the brain
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.


n amitriptilina
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
References in periodicals archive ?
Drug Original indication AAS Non-steroidal Anti-inflammatory Amitriptiline Antidepressant Auranofin Rheumatoidarthritis Chlorpromazine Anti-psychotic Clofazime Tuberculosis Clomipramine Antidepressant Disulfiram Alcoholism Ebselen Neuroprotector Escitalopram Antidepressant Fluoxetine Antidepressant Ibuprofen Non-steroidalAnti-inflammatory Iproniazid Antidepressant Loperamide Diarrhoea Sertraline Antidepressant Paroxetine Antidepressant Risperidone Anti-psychotic Simvastatin and Cardiovascular diseases Atorvastatin Thalidomide Anti-nausea Drug New indication AAS MRSA Amitriptiline Staphylococcus spp.
Products used in this study were of analytical quality and included amitriptiline hydrochloride 25 mg (Qualitest Pharmaceuticals Inc, Malvern, PA, USA); penicillin G and sildenafil citrate (Viagra) (Pfizer Inc, USA); estradiol and progesterone (Sigma Chemicals, USA); bioassay kits for FSH (DRG Diagnostics, Germany), LH (DRG Diagnostics, Germany), testosterone (Omega Diagnostics LTD, Scotland, UK); ethyl-ether (Mark and Baker LTD, Dagenham, England), and NaCl which were all purchased and handled under recommended conditions until used.
While imipramine, amitriptiline, nortriptiline, desipramine, maprotiline and doxepin can pot considerably prolong QTc, clinical studies have shown only a slight prolongation of QTc with the use of clomipramine, mirtazapine and trazodone and especially in cases of trazodone overdose.