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Related to Ampholytes: isoelectric point, zwitterion


 (zwĭt′ər-ī′ən, swĭt′-, tsvĭt′-)
A molecule, especially an amino acid, containing a positively charged ion at one end and a negatively charged ion at the other.

[German : Zwitter, hybrid (from Middle High German zwitarn, from Old High German, from zwi-, twice; see dwo- in Indo-European roots) + Ion, ion (from Greek; see ion).]

zwit′ter·i·on′ic (-ī-ŏn′ĭk) adj.


(Chemistry) chem an ion that carries both a positive and a negative charge
[C20: from German Zwitter hermaphrodite + ion]
zwitterionic adj


(ˈzwɪt ərˌaɪ ən, ˈswɪt-, ˈtsvɪt-)

an ion with both a positive and a negative charge.
[< German Zwitterion (1897) =Zwitter hybrid, hermaphrodite + Ion ion]
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References in periodicals archive ?
The isoelectric focusing (IEF) was performed without ampholytes and glycerol according to the manufacturer's instructions for peptide focusing.
Although gel-based techniques for protein separation are tremendously powerful, the observation of protein bands reflects a complex set of interactions between protein, ampholytes, buffer composition, gel composition, and pore size.
5M Urea, 4% NP-40, 5% (v/v) 2-mercaptoethanol, 2% v/v ampholytes of pH 5-8 and pH 3-10.
The isoelectric focusing of proteins can be determined using immobilized pH gradients or ampholytes.
Ampholytes were removed by bringing each fraction to 1 M NaCl for 15 min and then aliquots of 10-20 [micro]L of each fraction were used for protein analysis.
Proteins are ampholytes, exhibiting amphoteric behavior owing to the presence of both positively- and negatively-charged side chain groups distributed along the length of the molecule and at its ends.
0 ml ampholytes (pH gradient 4-5; Crescent Chemical, Hauppa, NY), 4.