aneuploidy

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an·eu·ploid

 (ăn′yə-ploid′)
adj.
Having a chromosome number that is not a multiple of the haploid number for the species.
n.
A cell or an organism characterized by an aneuploid chromosome number.


an′eu·ploi′dy (-ploi′dē) n.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.aneuploidy - an abnormality involving a chromosome number that is not an exact multiple of the haploid number (one chromosome set is incomplete)
abnormalcy, abnormality - an abnormal physical condition resulting from defective genes or developmental deficiencies
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
Translations
aneuploïdie
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References in periodicals archive ?
Advancing age has differential effects on DNA damage, chromatin integrity, gene mutations, and aneuploidies in sperm.
(1) The most common numerical variations of chromosomes recognized in prenatal samples are 13, 18, or 21 trisomies and sex chromosome aneuploidies, representing approximately 70% of all chromosomal anomalies detected.
Natera presented data at the Society for Maternal-Fetal Medicine Annual Pregnancy Meeting showing strong clinical performance of its Panorama SNP-based non-invasive prenatal test to detect common chromosomal aneuploidies in all women, including women under 35 years of age, with high accuracy.
Several studies have investigated the efficacy of the first trimester combined screening and insist on its acceptable detection rate of common aneuploidies {i.e.
(9) which involves SD sequences between test and control chromosomes to detect aneuploidies. SDs are two similar sequences with different fragment lengths, located on two different chromosomes.
Yet, as Dharajiya and colleagues demonstrate in this issue of Clinical Chemistry (2), incidental detection of maternal neoplasia is possible while performing prenatal whole genome DNA sequencing to screen for fetal chromosomal aneuploidies. Not only is it possible, it is not uncommon.
The quantitative fluorescence polymerase chain reaction and fluorescence in situ hybridization technique (FISH) screen the common aneuploidies (chromosomes 13, 18, 21 and XY) in affected foetuses.
Regarding high ovarian response, preliminary studies have suggested that it could be a determining factor in the genesis of aneuploidies, more than the gonadotropin doses used.
Early and accurate diagnosis of fetal aneuploidies is one of the cornerstones of fetal medicine.
The cell-free fetal DNA testing enables the parents to get information about general survivable fetal aneuploidies with a high accuracy and without any diagnostic procedure risk.