Following the Amerithrax attacks in 2001, a variety of federal, postal, and privately owned buildings in Washington, DC; New York; New Jersey; and Florida were contaminated with resilient Bacillus anthracis
Inhalational anthrax is caused by breathing in Bacillus anthracis
spores, which can occur after exposure to infected animals or contaminated animal products, or as a result of an intentional release of spores.
infection in humans has typically been classified as cutaneous, gastrointestinal, or inhalational on the basis of the bacterium's route of entry (1).
by binding to protective antigen (PA), the dominant antigen in anthrax infection, or lethal factor (LF)-proteins that work in combination to produce deadly anthrax toxins.
infects a human or animal, both toxins seek out and bind to receptors on the surfaces of human and animal cells.
On September 18, 2001, letters containing spores of the Ames strain of Bacillus anthracis
were mailed to the offices of news media.
coli, Salmonella, Mycobacterium tuberculosis, and Bacillus anthracis
, the bacterium that causes anthrax, as well as sensors that can detect various viruses, including the influenza virus.
Their topics include the outer structure of the Bacillus anthracis
spore, the genome, iron acquisition by the bacteria, anthrax toxins, interactions with macrophages, dissemination through hosts, vaccines, and anthrax as a weapon of war and terrorism.
The technology can also be used to remove Bacillus anthracis
spores from egg whites.
showed the highest sensitivity to all the extracts with the highest zone of inhibition (33mm).
This easy-to-use, automated, and highly accurate real-time PCR (polymerase chain reaction) instrument could detect as few as 30 Bacillus anthracis
spores in a U.
Recently our laboratories have designed and tested assays for chromosomal genes (Bacillus anthracis
gyrA GenBank accession no.