Blood count, sedimentation rate, biochemical parameters, protein electrophoresis, levels of immunoglobulin, complement, antistreptolysin O, C-reactive protein, rheumatoid factor, anti-nuclear antibody
, anti-deoxyribonucleic acid levels, tumor markers, and thyroid function tests were all within normal limits.
ANA antibodies were detected through Mouse Anti-nuclear antibody
(ANA) ELISA kit (Catalogue # GA-E0266MS) purchased from GenAsia.
M2 PHARMA-June 12, 2017-Technavio Predicts 7% Growth in Global Anti-nuclear Antibody
(ANA), ribonucleoprotein (RNP), Sjogren-syndrome--related antigen A (SS-A), Sjogren-syndrome--related B (SS-B), scleroderma antibodies, anti-dsDNA, anti-Smith antibody, thyroglobulin antibody, and anti-thyroid peroxidase antibodies were negative.
The anti-nuclear antibody
test was positive at a titre of 1:2 560, as was the anti-U1RNP antibody, and anti-Ro antibody.
The most helpful markers for diagnosing WG are by far anti-nuclear antibody
(ANA), cytoplasmic antineutrophil cytoplasmic antibody (c-ANCA), and anti-proteinase 3 antibodies (anti-PR3).
The anti-nuclear antibody
was weakly positive at a titer of 1:40, while the anti-smooth muscle antibody, anti-mitochondrial antibody and anti-liver kidney microsomal antibody were all negative.
Laboratory findings in patients with levamisole-induced vasculitis include leukopenia (leukocyte count <4000/[micro]L), neutropenia (neutrophil count <1500/[micro]L), agranulocytosis (neutrophil count <500/[micro]L), elevated erythrocyte sedimentation rate, normal coagulation studies, and positive autoantibodies including p- and c-ANCAs, anti-nuclear antibody
, and lupus anticoagulant.
High levels of anti-nuclear antibody
(ANA) and anti-neutrophilic cytoplasmic antibody (ANCA) and other connective tissue antibodies in patients with autoimmune thyroid disorder and ophthalmopathy support the view that "Graves' disease is a collagen-like disorder.
The following tests were performed in all study participants for the study purposes: anti-nuclear antibody
(ANA) anti-double stranded DNA (anti- dsDNA) anti-liver/kidney microsomal type 1 (LKM-1) anti-smooth muscle antibody (Anti-SMA) antimitochondrial antibodies (AMA) perinuclear antineutrophil cytoplasmic antibody (p-ANCA) cytoplasmic ANCA (c-ANCA) anti-SSA/Ro anti- SSB/La anti-Scl-70 anti-centromere antibody Anti-Jo-1 anti-thyroid peroxidase (anti-tpo) Anti thyroglobulin (anti-Tg) Anti-U1small nuclear (sn) RNP (Anti-U1snRNP) Anti Smith antibody (Anti- Sm) and anti-cardiolipin antibodies (ACA).
(ANA) positivity was seen in 80% of the patients.
Studies for c-ANCA, anti-proteinase 3 (PR3), anti-GBM, cryoglobulins, complement levels, anti-nuclear antibody
, rheumatoid factor, hepatitis A, B, and C, and creatinine kinase were normal.